Enhanced Population-based Core Surveillance of Meningococcal Invasive Infections at Participating Centers Across Canada

NCT ID: NCT04184336

Last Updated: 2022-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2022-12-31

Brief Summary

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Active metropolitan area surveillance for hospital admissions related to invasive infection with Neisseria meningitidis will be conducted at the 12 centers in the IMPACT network in collaboration with Public Health officials, local infection specialists and infection control practitioners during the interval from January 1, 2016 to December 31, 2022.

Detailed Description

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The objectives are 3-fold, including:

1. description of affected children and adults and the nature and outcome of the infection episodes
2. incidence rate determination in defined populations, by age, serogroup and study year
3. detailed study of the organisms recovered from cases

Conditions

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Invasive Meningococcal Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Persons of all ages

Persons of all ages admitted between January 1, 2016 and December 31, 2022 with a positive result of Neisseria meningitidis isolated or detected by PCR from a normal sterile site, such as blood, CSF, joint fluid, pleural, peritoneal, pericardial fluid or tissue biopsy

surveillance

Intervention Type OTHER

Interventions

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surveillance

Intervention Type OTHER

Eligibility Criteria

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Exclusion Criteria

1. clinical signs, gram stain, or antigen test
2. meningococci isolated only from respiratory tract, including conjunctiva, sinuses, middle ear/mastoid, throat, peritonsillar abscess, cervical lymph node, tracheal aspirate, bronchial lavage etc -
Minimum Eligible Age

1 Minute

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role collaborator

GlaxoSmithKline

INDUSTRY

Sponsor Role collaborator

Canadian Paediatric Society

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Alberta Children's Hospital

Calgary, Alberta, Canada

Site Status RECRUITING

Stollery Children's Hospital

Edmonton, Alberta, Canada

Site Status RECRUITING

BC Children's Hospital

Vancouver, British Colombia, Canada

Site Status RECRUITING

Children's Hospital Research Institute of Manitoba

Winnipeg, Manitoba, Canada

Site Status RECRUITING

Eastern Health Janeway Children's and Rehabilitation Centre

St. John's, Newfoundland and Labrador, Canada

Site Status RECRUITING

IWK Health Centre

Halifax, Nova Scotia, Canada

Site Status RECRUITING

Children's Hospital of Eastern Ontario

Ottawa, Ontario, Canada

Site Status RECRUITING

The Hospital for Sick Children

Toronto, Ontario, Canada

Site Status RECRUITING

CHU- Sainte Justine

Montreal, Quebec, Canada

Site Status RECRUITING

Montreal Children's Hospital

Montreal, Quebec, Canada

Site Status RECRUITING

Centre Mere-Enfant Soleil CHU de Quebec

Québec, Quebec, Canada

Site Status RECRUITING

Royal University Hospital

Saskatoon, Saskatchewan, Canada

Site Status RECRUITING

McMaster's Children Hospital

Hamilton, , Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Melanie Laffin Thibodeau

Role: CONTACT

613-526-9397 ext. 239

Marie Adele Davis

Role: CONTACT

613-526-9397

Facility Contacts

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Taj Jadavji, MD

Role: primary

Wendy Vaudry, MD

Role: primary

Manish Sadarangani

Role: primary

Joanne Embree, MD

Role: primary

Natalie Bridger, MD

Role: primary

Karina Top, MD

Role: primary

Nicole Le Saux, MD

Role: primary

Shaun Morris, MD

Role: primary

Marc Lebel, MD

Role: primary

Jesse Papenburg, MD

Role: primary

Roseline Thibeault, MD

Role: primary

Ben Tan

Role: primary

Jeffrey Pernica, MD

Role: primary

Provided Documents

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Document Type: Study Protocol: Study protocol

View Document

Document Type: Study Protocol: ID_NCT04184336

View Document

Related Links

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http://www.cps.ca/en/impact

Description IMPACT public website

Other Identifiers

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MENING

Identifier Type: -

Identifier Source: org_study_id

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