Cord Blood Microtransplantation for Treatment of Acute Myeloid Leukemia

NCT ID: NCT04174586

Last Updated: 2020-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-22

Study Completion Date

2024-08-31

Brief Summary

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Discuss the effectiveness and safety of cord blood microtransplantation for treatment of acute myeloid leukemia

Detailed Description

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The investigators conducted a prospective, single center clinical trial to dissuss the outcomes and toxicities of HLA-mismatched cord blood infusion after chemotherapy (microtransplantation) in older patients with acute myeloid leukemia (AML)

Conditions

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Safety Issues Efficiency

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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cord blood group

standard induction and consolidation chemotherapy with cord blood microtransplantation

Group Type EXPERIMENTAL

microtransplantation

Intervention Type BIOLOGICAL

HLA mismatched donor cord blood infusion

Interventions

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microtransplantation

HLA mismatched donor cord blood infusion

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

1. de novo acute myeloid leukemia
2. age 60-80

Exclusion Criteria

1. have no suitable donor or donor refused
2. patient refused to accept donor cells
Minimum Eligible Age

60 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Hospital of the Chinese Academy of Military Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zimin Sun

Role: STUDY_CHAIR

The First Affiliated Hospital of USTC

Locations

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The First Affiliated Hospital of USTC

Hefei, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Wen Yao

Role: CONTACT

055162283730 ext. 055162283730

Facility Contacts

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Wen Yao

Role: primary

055162283730 ext. 055162283730

Other Identifiers

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CB-001

Identifier Type: -

Identifier Source: org_study_id

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