Acupuncture With Press Tack Needles for Perioperative Pain After Open Radical Prostatectomy

NCT ID: NCT04172649

Last Updated: 2023-04-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-01

Study Completion Date

2021-12-31

Brief Summary

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Acupuncture has been shown in several meta-analyses and clinical studies, in different surgical settings and chronic back pain, to be a safe adjuvant option for postoperative pain treatment. In this study, the investigator hypothesize that acupuncture can decrease postoperative pain intensity and amount of given analgesics, and accelerate recovery of bowel motility, in patients after open radical prostatectomy.

The investigator will also investigate whether or not acupuncture with needle skin penetration is more efficacious than acupressure.

Detailed Description

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This study will be a randomized, controlled and partially blinded study with three arms: 1) press tack needle acupuncture (ACU) and routine postoperative analgesic care, 2) press tack placebo acupressure (SHAM) and routine postoperative analgesic care, and 3) only routine postoperative analgesic care (CONTROL).

Conditions

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Prostate Cancer Perioperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Acu Arm

press tack needle acupuncture (ACU) and routine postoperative analgesic care

Group Type EXPERIMENTAL

Acupuncture

Intervention Type OTHER

On the day before surgery, patients randomized to the intervention groups will receive routine postoperative analgesic care with application of 6 bilateral press tack needles (diameter of 0.15mm and length of 0.6mm for P-6 and Shenmen, diameter of 0.20mm and length of 1.2mm for SP-6, Seirin New Pyonex, Seirin Corp., Shizuoka City, Japan).

SHAM Arm

press tack placebo acupressure (SHAM) and routine postoperative analgesic care

Group Type SHAM_COMPARATOR

Acupressure

Intervention Type OTHER

On the day before surgery, patients randomized to the intervention groups will receive routine postoperative analgesic care with application of 6 bilateral press tack placebos (knob without needle, diameter of 0.15mm and length of 0.6mm for P-6 and Shenmen, diameter of 0.20mm and length of 1.2mm for SP-6, Seirin New Pyonex, Seirin Corp., Shizuoka City, Japan).

CONTROL Arm

Patients in the control group will receive only routine postoperative analgesic care

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Acupuncture

On the day before surgery, patients randomized to the intervention groups will receive routine postoperative analgesic care with application of 6 bilateral press tack needles (diameter of 0.15mm and length of 0.6mm for P-6 and Shenmen, diameter of 0.20mm and length of 1.2mm for SP-6, Seirin New Pyonex, Seirin Corp., Shizuoka City, Japan).

Intervention Type OTHER

Acupressure

On the day before surgery, patients randomized to the intervention groups will receive routine postoperative analgesic care with application of 6 bilateral press tack placebos (knob without needle, diameter of 0.15mm and length of 0.6mm for P-6 and Shenmen, diameter of 0.20mm and length of 1.2mm for SP-6, Seirin New Pyonex, Seirin Corp., Shizuoka City, Japan).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Males aged 18-70 years
* Diagnosis with prostate cancer and scheduled for open radical prostatectomy
* Ability and willingness to follow study instructions and complete all required questionnaires during hospitalization and follow-up
* Written informed consent

Exclusion Criteria

* Inability to understand the terms of this study
* Simultanously participation in other clinical trials possibly influencing primary or secondary endpoints or any acupuncture-related clinical trials within 30 days prior to inclusion

* Prior surgery within the last three months
* Received acupuncture within 6 weeks before surgery
* Known hypersensitivity or fear of acupuncture
* Known abuse of drugs, medications and alcohol
* Chronic pain for more than 3 months
* Continuous opioid analgesic medications for more than 3 days during the 4 weeks prior to surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Seirin Corporation, Shizuoka City, Japan

UNKNOWN

Sponsor Role collaborator

Martini-Klinik am UKE GmbH

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hans Heinzer, Prof.

Role: PRINCIPAL_INVESTIGATOR

Vice Medical Director and Faculty member of Martini-Klinik

Locations

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Martini-Klinik am UKE GmbH

Hamburg, , Germany

Site Status

Countries

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Germany

Other Identifiers

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DRK S00019884

Identifier Type: REGISTRY

Identifier Source: secondary_id

AcuPro 09.2019

Identifier Type: -

Identifier Source: org_study_id

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