Crural Dissection in Sleeve Gastrectomy

NCT ID: NCT04168060

Last Updated: 2025-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

124 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-22

Study Completion Date

2025-05-28

Brief Summary

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The purpose of this study is to identify if there is a benefit in routine dissection of the diaphragmatic crura during sleeve gastrectomy.

Detailed Description

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Conditions

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Sleeve Gastrectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Crura Dissection

Participants with a visually detectable hiatal hernia at the time of sleeve gastrectomy procedure will undergo a crura dissection and hiatal hernia repair.

Group Type EXPERIMENTAL

Sleeve gastrectomy

Intervention Type PROCEDURE

Surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature.

Hiatal hernia repair

Intervention Type PROCEDURE

This involves tightening the opening in your diaphragm with stitches to keep your stomach from bulging upward through the opening in the muscle wall.

Crura dissection

Intervention Type PROCEDURE

The diaphragmatic crura, one of two tendon structures below the diaphragm, will be removed during the laparoscopic sleeve gastrectomy.

National Practice

Participants with no detectable hiatal hernia will be randomized to either Group 2 or 3. Group 2 participants will be treated to the national practice patterns of complete dissection of the curvature of the stomach without dissection of the crura.

Group Type EXPERIMENTAL

Sleeve gastrectomy

Intervention Type PROCEDURE

Surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature.

Standard of Care

Participants with no detectable hiatal hernia will be randomized to either Group 2 or 3. Group 3 participants will undergo the institutional standard of care with the dissection of the crura.

Group Type EXPERIMENTAL

Sleeve gastrectomy

Intervention Type PROCEDURE

Surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature.

Crura dissection

Intervention Type PROCEDURE

The diaphragmatic crura, one of two tendon structures below the diaphragm, will be removed during the laparoscopic sleeve gastrectomy.

Interventions

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Sleeve gastrectomy

Surgical weight-loss procedure in which the stomach is reduced to about 15% of its original size, by surgical removal of a large portion of the stomach along the greater curvature.

Intervention Type PROCEDURE

Hiatal hernia repair

This involves tightening the opening in your diaphragm with stitches to keep your stomach from bulging upward through the opening in the muscle wall.

Intervention Type PROCEDURE

Crura dissection

The diaphragmatic crura, one of two tendon structures below the diaphragm, will be removed during the laparoscopic sleeve gastrectomy.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. All patients undergoing primary sleeve gastrectomy at the University of Miami Division of Bariatric surgery
2. Age between 18-69 years
3. Able to provide consent

Exclusion Criteria

1. History of anti-reflux procedure
2. History of foregut surgery
3. Narcotic dependence
4. History of gastroparesis
5. Special/vulnerable populations such as minors, patients unable to consent, pregnant women, and prisoners will not be included in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Nestor De La Cruz-Munoz

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nestor De La Cruz-Munoz, MD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami Medical Campus

Miami, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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20190190

Identifier Type: -

Identifier Source: org_study_id

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