AXONE-Acute II: Acute Assessment of a Micro Multipolar Lead for Enhanced Cardiac Resynchronisation Therapy

NCT ID: NCT04156412

Last Updated: 2020-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-02

Study Completion Date

2020-10-31

Brief Summary

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Pilot study to evaluate the performance of a lead below 2 French with specific distal shape to deliver efficient LV pacing

Detailed Description

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Conditions

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Cardiac Resynchronisation Therapy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Implant test procedure

Implant test procedure with new LV quadripolar lead before a standard implantation for Cardiac resynchronisation therapy

Group Type EXPERIMENTAL

Implant test procedure

Intervention Type DEVICE

Implant test procedure with new LV quadripolar lead before a standard implantation for Cardiac resynchronisation therapy

Interventions

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Implant test procedure

Implant test procedure with new LV quadripolar lead before a standard implantation for Cardiac resynchronisation therapy

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female patient aged ≥18 years old.
* Patient presenting a CRT-P or CRT-D indication according to the latest ESC guidelines1.
* Primary implant of a CRT device (including upgrade from a single or dual-chamber pacemaker or ICD).
* Signed and dated informed consent.

Exclusion Criteria

* Class IV of NYHA (ambulatory or not).
* Allergy to contrast media used for imaging during cardiac catheterization.
* Severe Renal Failure (clearance of creatinine according to Modification of diet in renal disease formula (MDRD) \< 30ml/mn/m²).
* Previous failure of catheterization of the coronary sinus, or previous failure of left ventricular lead implantation.
* Already included in another clinical study involving intra-cardiac active implantable device, or participation to any other clinical trial in the last 2 weeks.
* Vulnerable patient such as person deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision).
* Known pregnancy, breastfeeding or women in childbearing age without an adequate contraceptive method with a known failure rate \< 1%.-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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MicroPort CRM

INDUSTRY

Sponsor Role collaborator

University Hospital, Rouen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frédéric ANSELME, Pr

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Rouen

Locations

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Bordeaux University Hospital

Bordeaux, , France

Site Status RECRUITING

Clermont-Ferrand University Hospital

Clermont-Ferrand, , France

Site Status RECRUITING

Lille University Hospital

Lille, , France

Site Status RECRUITING

Rennes University Hospital

Rennes, , France

Site Status RECRUITING

Rouen University Hospital

Rouen, , France

Site Status RECRUITING

Hospital Universitari Germans Trias i Pujol

Badalona, , Spain

Site Status RECRUITING

Hospital Universitario y Politécnico La Fe

Valencia, , Spain

Site Status RECRUITING

Countries

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France Spain

Central Contacts

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Frédéric ANSELME, Pr

Role: CONTACT

+3323288 ext. 8990

Julien BLOT

Role: CONTACT

+3323288 ext. 8265

Facility Contacts

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Philippe RITTER, Pr

Role: primary

Frédéric Jean, MD

Role: primary

Didier KLUG, Pr

Role: primary

Christophe LECLERCQ, Pr

Role: primary

Frédéric ANSELME, Pr

Role: primary

Roger VILLUENDAS, MD

Role: primary

Joaquín OSCA, MD

Role: primary

Other Identifiers

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2019/127/HP

Identifier Type: -

Identifier Source: org_study_id

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