Quality of Life, Unmet Needs and Satisfaction With Care After Vulvar Cancer

NCT ID: NCT04152512

Last Updated: 2023-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

153 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-29

Study Completion Date

2027-10-31

Brief Summary

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The aim of this prospective, longitudinal Swedish multi-center study is to assess the quality of life, treatment-related morbidity, unmet needs and satisfaction with care after treatment for vulvar cancer, evaluated by a validated questionnaire.

Detailed Description

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PRIMARY OBJECTIVES:

Information about:

* General and vulvar-cancer-specific quality of life before and after any treatment for newly diagnosed vulvar cancer
* Treatment-related morbidity after any treatment for newly diagnosed vulvar cancer
* Unmet needs of patients with newly diagnosed vulvar cancer
* Satisfaction with care after any treatment for newly diagnosed vulvar cancer in Sweden.

OUTLINE:

The study is planned as a prospective, longitudinal multi-centre study in Sweden. Since 2017, the treatment of vulvar cancer patients has been accredited to four tertiary referral university hospitals in Sweden; the Sahlgrenska University hospital in Gothenburg, the Linköping University hospital, the Skåne University hospital in Lund and the Karolinska University hospital in Stockholm.

150 patients are estimated for inclusion during a time frame of about 18 months.

Eligible patients will be asked to complete a validated questionnaire at different points of time (before and after treatment). Calculating a response rate of about 50% - 60%, this will result in at least 80 completed questionnaires.

The questionnaires consist of the following parts:

* European Organisation for Research and Treatment of Cancer (EORTC)-QLQ-C30
* European Organisation for Research and Treatment of Cancer (EORTC)-QLQ-VU-34 (Vulva-specific module)
* Hospital Depression and Anxiety Scale (HADS)
* Supportive Care Needs Survey Short Form, excerpt (SCNS-SF34)
* European Organisation for Research and Treatment of Cancer (EORTC)-PATSAT (Patient Satisfaction), excerpt
* Demographic data
* 25 self-constructed (and validated) questions

RESULTS:

Results are expected to be available in 2021.

Conditions

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Vulvar Cancer Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Whole Cohort

Whole cohort administration of questionnaire at 7 times

Questionnaire administration

Intervention Type BEHAVIORAL

Questionnaire administration (4 different forms: pre-treatment, 3-4 months after treatment, 1 year after treatment, 2-5 years (yearly) after treatment

Interventions

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Questionnaire administration

Questionnaire administration (4 different forms: pre-treatment, 3-4 months after treatment, 1 year after treatment, 2-5 years (yearly) after treatment

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Primary diagnosis of vulvar cancer, all stages, all planned treatments
* Informed consent

Exclusion Criteria

* Disability to understand and complete the questionnaire due to language difficulties, severe psychiatric illness or dementia
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Linkoeping

OTHER

Sponsor Role collaborator

Skane University Hospital

OTHER

Sponsor Role collaborator

Sahlgrenska University Hospital

OTHER

Sponsor Role collaborator

Karolinska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Diana Zach

MD, senior consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Diana Zach, MD

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden

Locations

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Karolinska University Hospital

Stockholm, Stockholm County, Sweden

Site Status

Sahlgrenska University Hospital

Gothenburg, , Sweden

Site Status

Linkopings University Hospital

Linköping, , Sweden

Site Status

Skanes University Hospital Lund

Lund, , Sweden

Site Status

Countries

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Sweden

References

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Zach D, Jensen PT, Falconer H, Kolkova Z, Bohlin KS, Kjolhede P, Raices Cruz I, Avall-Lundqvist E, Floter Radestad A. The impact of local symptoms on health-related quality of life in vulvar cancer survivors-A nationwide prospective study. Acta Obstet Gynecol Scand. 2025 Aug;104(8):1517-1529. doi: 10.1111/aogs.15164. Epub 2025 Jun 9.

Reference Type DERIVED
PMID: 40490985 (View on PubMed)

Other Identifiers

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2018/1402-31/1

Identifier Type: -

Identifier Source: org_study_id

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