Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women

NCT ID: NCT04125940

Last Updated: 2021-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-14

Study Completion Date

2019-12-30

Brief Summary

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This study evaluates acute ingestion of the dietary supplement Resync on blood nitrate/nitrite concentrations in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.

Detailed Description

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The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid. Manufacturers of Resync recommend users take this product 60-90 minutes before an athletic event or 30-90 minutes after exercise. Resync bases these claims on prior studies investigating the individual ingredients' abilities to increase blood nitrate/nitrite levels; however, there are no clinical trials on the finished product itself.

The purpose of this pilot study is to determine the impact of acute, single ingestion of Resync products on blood nitrate/nitrite concentration in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Single-blind, pre-post ingestion, control
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants
Single-Blind

Study Groups

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Placebo-controlled Arm

Placebo - 12oz water with food coloring

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

12oz water + food coloring

1 serving Resync Arm

12oz water + 7.5g Resync

Group Type ACTIVE_COMPARATOR

Resync

Intervention Type DIETARY_SUPPLEMENT

The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid.

2 servings Resync Arm

12oz water + 15g Resync

Group Type ACTIVE_COMPARATOR

Resync

Intervention Type DIETARY_SUPPLEMENT

The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid.

1 servings Resync+Collagen Arm

12oz water + 17g collagen + 2g Resync + 1g Carbohydrates

Group Type ACTIVE_COMPARATOR

Resync + Collagen

Intervention Type DIETARY_SUPPLEMENT

17g Collagen + 2g Resync + 1g Carbohydrate

Interventions

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Resync

The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid.

Intervention Type DIETARY_SUPPLEMENT

Resync + Collagen

17g Collagen + 2g Resync + 1g Carbohydrate

Intervention Type DIETARY_SUPPLEMENT

Placebo

12oz water + food coloring

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* BMI 18 - 29.9 kg/m2
* Non-smoker
* Non-vegan
* Not using nitrate-based dietary supplements

Exclusion Criteria

* Diagnosed history of diabetes
* Diagnosed history of cardiovascular disease
* Diagnosed history of neurological disease
* Pregnant females
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Resync, LLC

UNKNOWN

Sponsor Role collaborator

University of Memphis

OTHER

Sponsor Role lead

Responsible Party

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Richard Bloomer

Dean of School of Health Studies

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Richard J Bloomer, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Dean of School of Health Studies

Locations

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Center for Nutraceutical and Dietary Supplement Research

Memphis, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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PRO-FY2020-67

Identifier Type: -

Identifier Source: org_study_id

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