Gastric Slow Wave and Autonomic Nervous Function in Cirrhotic Patients With Esophageal Varices After Ligation-A Clinical Research

NCT ID: NCT04125875

Last Updated: 2019-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

28 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-05-23

Study Completion Date

2019-07-31

Brief Summary

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This study is intended to include 20 patients with esophageal varices caused by liver cirrhosis who were admitted to the first affiliated hospital of nanjing medical university from May 2019, and randomly select 8 patients with gastric polyps as the control group.General clinical data, imaging data, endoscopic data and laboratory indicators were collected.Electrogastrogram (EGG) and Heart Rate Variability (HRV) were performed before and 24 hours after operation in patients with cirrhotic esophageal varices, and the dyspepsia scale was filled out.Electrogastrogram (EGG) and cardiac variability (HRV) were performed in patients with gastric polyps 24 hours before and after surgery, and the dyspepsia scale was filled.EGG uses the surface electrode to record gastric myoelectric activity, and evaluates the patient's gastric rhythm by normal slow wave ratio, overspeed ratio, overslow ratio, and rhythm disorder ratio.The HRV evaluates the balance state of the patient's autonomic nervous system with High Frequency (HF)/Low Frequency (LF).SPSS software was used for paired sample analysis of experimental results.

Detailed Description

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Conditions

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Esophageal Varices in Cirrhosis of the Liver

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with cirrhosis of esophageal varices

Electrogastrogram(EGG)

Intervention Type DIAGNOSTIC_TEST

Heart Rate Variability

Heart Rate Variability(HRV)

Intervention Type DIAGNOSTIC_TEST

Heart Rate Variability

Patients with gastric polyps

Electrogastrogram(EGG)

Intervention Type DIAGNOSTIC_TEST

Heart Rate Variability

Heart Rate Variability(HRV)

Intervention Type DIAGNOSTIC_TEST

Heart Rate Variability

Interventions

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Electrogastrogram(EGG)

Heart Rate Variability

Intervention Type DIAGNOSTIC_TEST

Heart Rate Variability(HRV)

Heart Rate Variability

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients over 18 years old with cirrhosis of esophageal varices who underwent endoscopic ligation
* Signed informed consent

Exclusion Criteria

* Hemorrhage in the digestive tract, unstable vital signs
* Hepatic encephalopathy
* Unwilling to cooperate with the examiner
* Skin allergies
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First Affiliated Hospital with Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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First Affiliated Hospital of Nanjing Medical Universit

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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2019-SR-086

Identifier Type: -

Identifier Source: org_study_id

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