Study on Adhesion Properties of Three Different Adhesives

NCT ID: NCT04125797

Last Updated: 2019-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-07

Study Completion Date

2019-10-31

Brief Summary

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This clinical investigation is a single centre, double blinded, case control study in healthy adult females. This study will be conducted in private rooms at Gentofte Hospital (Hjerte-medicinsk Forskning, post 835, Kildegårdsvej 28, 2900 Hellerup).

The investigation centre will enroll 39 subjects including a 20% drop out within a four (4) months period. The subject will not be enrolled before approval of investigation protocol by the local ethics committee.

The subjects need to meet the inclusion and exclusion criteria to be included in this clinical investigation. Each volunteer enrolled in the investigation can only participate once in a procedure. The testing period for each subject will be minimum 72 hours.

The principal investigator's qualifications will be verified through his/her CV. The principal investigator is required to be a medical doctor with at least one year's experience in using similar medical adhesives (e.g. by being experienced in using electrodes where medical adhesives are included) and at least one year's experience with clinical research. In addition, the investigator must be trained in GCP before the study is initiated.

If any subject withdraws from the study, they will not be replaced as drop-out rate is included in the sample size.

Subjects must show up for two sessions, in the first session six adhesives will be placed below the subjects bra. The adhesives will be removed after minimum 72 hours at the second visit. While wearing the adhesives the subjects must keep the investigational area dry. 24, 48 and 72 hours after placement of the adhesives, the subject is asked to completed a questionnaire.

The eCRF must be completed for each subject that has signed the Informed consent form (ICF) and enrolled into this clinical investigation.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Adhesive 1

This arm investigates one type of silicone adhesive (3M2475P) on adult female skin.

Group Type ACTIVE_COMPARATOR

Application of adhesive

Intervention Type OTHER

Adhesive will be placed on the subjects skin below the bra. Placement of the adhesive will be randomized.

Adhesive 2

This arm investigates one type of silicone adhesive (RX1449P) on adult female skin.

Group Type ACTIVE_COMPARATOR

Application of adhesive

Intervention Type OTHER

Adhesive will be placed on the subjects skin below the bra. Placement of the adhesive will be randomized.

Adhesive 3

This arm investigates one type of silicone adhesive (PS-1243) on adult female skin.

Group Type ACTIVE_COMPARATOR

Application of adhesive

Intervention Type OTHER

Adhesive will be placed on the subjects skin below the bra. Placement of the adhesive will be randomized.

Interventions

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Application of adhesive

Adhesive will be placed on the subjects skin below the bra. Placement of the adhesive will be randomized.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female Healthy Volunteers.
* Age 18 - 40 years old.
* Willing to attend two scheduled visits
* Able to assess itch and adherence at 24h, 48h and 72h.
* Provide written informed consent.

Exclusion Criteria

* Non-intact skin barrier (e.g. eczema, rash, cut, scar tissue, wound, etc.).
* History of inflammatory skin diseases (e.g. atopic dermatitis or psoriasis).
* History of contact allergy
* Swimming or engaging in sport activities causing sweat during study peri-od. v. Use of medication (e.g. corticosteroids) which could affect skin reactions.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ambu A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Gentofte Hospital

Hellerup, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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CIS-015

Identifier Type: -

Identifier Source: org_study_id

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