Efficacy of Extract of Trigonella Foenum-graceum as Topical Phytoestrogen in Skin Aging Treatment of Post Menopausal Women
NCT ID: NCT04123743
Last Updated: 2020-07-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1/PHASE2
21 participants
INTERVENTIONAL
2019-08-10
2019-11-10
Brief Summary
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Detailed Description
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The study will be held in esthetic cluster, Kencana Cipto Mangunkusumo Hospital, and radiology cluster, Kencana Cipto Mangunkusumo Hospital from August 2019 until November 2019.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Experimental Group
The experimental group will be given topical cream containing Trigonella foenum-graceum extract, Wardah brand facial wash, and Parasol sunscreen SPF 33.
Trigonella foenum-graceum extract topical cream
Topical cream containing Trigonella foenum-graceum extract
Facial Wash
Wardah brand facial wash
Sunscreen Cream
Parasol sunscreen cream SPF 33
Control Group
The control / placebo group will be given placebo topical cream, Wardah brand facial wash, and Parasol sunscreen SPF 33
Facial Wash
Wardah brand facial wash
Sunscreen Cream
Parasol sunscreen cream SPF 33
Placebo
Placebo topical cream
Interventions
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Trigonella foenum-graceum extract topical cream
Topical cream containing Trigonella foenum-graceum extract
Facial Wash
Wardah brand facial wash
Sunscreen Cream
Parasol sunscreen cream SPF 33
Placebo
Placebo topical cream
Eligibility Criteria
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Inclusion Criteria
* Have skin aging problems that manifested as wrinkles on forehead, crow's feet, and nasolabial fold region
* Estradiol level \< 30 pg/mL
* Willing to terminate the routine use of facial cream or treatment during the study duration and at least for 30 days before the study commence
* Willing to follow the study protocol and sign the informed consent
Exclusion Criteria
* Using oral/topical hormonal supplement in the last 12 months
* Using products containing retinoic acid or it's derivatives in the last 30 days
* Underwent radiotherapy, facelift, dermabrasion, botox, or facial filler procedures in the last 5 years
* Breast lump or other breast abnormality
* History of cancer or malignancy
* Vein thrombosis
* History of hormonal contraception allergy
* History of ovariectomy
FEMALE
Yes
Sponsors
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Indonesia University
OTHER
Responsible Party
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Shannaz Nadia Yusharyahya
Head of Geriatric Dermatology Division, Department of Dermatovenereology, Faculty of Medicine, Indonesia University
Locations
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Faculty of Medicine, Universitas Indonesia
Jakarta Pusat, DKI Jakarta, Indonesia
Countries
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Other Identifiers
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00001
Identifier Type: -
Identifier Source: org_study_id
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