Oxytocin Effects on the Prosocial Learning

NCT ID: NCT04105140

Last Updated: 2019-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-01

Study Completion Date

2018-08-10

Brief Summary

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To investigate whether intranasal oxytocin (24 IU) treatment can influence prosocial learning behavior in males.

Detailed Description

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In a double-blind, within-subject, placebo controlled design, investigators plan to investigate the effect of oxytocin treatment on prosocial learning. Before the self-administration, participants need to finish several questionnaires including IRI, AAS, BASBIS, SPSRQ, SES, PTM, STAI, BDI, ASQ and PNAS. They would finish the PANAS again before the scanning.

Participants are informed that they perform the reward learning task either for themselves, another (unknown) person or no one (control). In the probabilistc reward learning task, associations with two stimuli with different reward probabilities are learned via monetary feedback (reward ¥1 or no reward ¥0). After the experiment, participants need to finish the PANAS.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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male oxytocin group

male subjects with oxytocin treatment

Group Type EXPERIMENTAL

Oxytocin

Intervention Type DRUG

intranasal administration of oxytocin (24 IU)

male placebo group

male subjects with placebo treatment

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

intranasal administration of placebo (24 IU)

Interventions

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Oxytocin

intranasal administration of oxytocin (24 IU)

Intervention Type DRUG

Placebo

intranasal administration of placebo (24 IU)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* without past or current psychiatric or neurological disorders

Exclusion Criteria

* history of head injury
* medical or psychiatric illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Keith Kendrick

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Keith Kendrick, Dr.

Role: PRINCIPAL_INVESTIGATOR

University of Electronic Science and Technology of China

Locations

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School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Site Status

Countries

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China

Other Identifiers

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UESTC-neuSCAN-44

Identifier Type: -

Identifier Source: org_study_id

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