Trial Outcomes & Findings for Information Visualizations to Facilitate HIV-related Patient-provider Communication in New York City (Info Viz: HIV-NYC) (NCT NCT04102540)

NCT ID: NCT04102540

Last Updated: 2021-09-17

Results Overview

Mean Cluster of Differentiation 4 (CD4) count at each time point.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

32 participants

Primary outcome timeframe

Baseline, 3-, and 6-months

Results posted on

2021-09-17

Participant Flow

Participant milestones

Participant milestones
Measure
Infographic Intervention Group
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Overall Study
STARTED
32
Overall Study
COMPLETED
24
Overall Study
NOT COMPLETED
8

Reasons for withdrawal

Reasons for withdrawal
Measure
Infographic Intervention Group
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Overall Study
Withdrawn by PI
2
Overall Study
Lost to Follow-up
6

Baseline Characteristics

Information Visualizations to Facilitate HIV-related Patient-provider Communication in New York City (Info Viz: HIV-NYC)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Age, Continuous
52.4 years
STANDARD_DEVIATION 14.19 • n=5 Participants
Sex/Gender, Customized
Male
18 Participants
n=5 Participants
Sex/Gender, Customized
Female
11 Participants
n=5 Participants
Sex/Gender, Customized
Other
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
30 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
4 Participants
n=5 Participants
Race (NIH/OMB)
White
4 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
12 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
10 Participants
n=5 Participants
Region of Enrollment
United States
30 Participants
n=5 Participants
Country of birth
United States
9 Participants
n=5 Participants
Country of birth
Dominican Republic
15 Participants
n=5 Participants
Country of birth
Other
6 Participants
n=5 Participants
Married or in a serious relationship
Married or in a serious relationship
7 Participants
n=5 Participants
Married or in a serious relationship
NOT married or in a serious relationship
23 Participants
n=5 Participants
Highest level of education completed
0-5 years of school
4 Participants
n=5 Participants
Highest level of education completed
6-8 years of school
6 Participants
n=5 Participants
Highest level of education completed
9-11 years of school
6 Participants
n=5 Participants
Highest level of education completed
Finished HS/ has GED
10 Participants
n=5 Participants
Highest level of education completed
University or other education past HS
4 Participants
n=5 Participants
New Patient
New patient
4 Participants
n=5 Participants
New Patient
Established patient
26 Participants
n=5 Participants
Years living with HIV
16.28 Years
STANDARD_DEVIATION 9.7 • n=5 Participants
Years attending the clinic
10.04 Years
STANDARD_DEVIATION 9.41 • n=5 Participants
Preferred language of participation
English-speaking
12 Participants
n=5 Participants
Preferred language of participation
Spanish-speaking
18 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn by the PI and were not included in analyses.

Mean Cluster of Differentiation 4 (CD4) count at each time point.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean CD4 Count
CD4 Count at Baseline
321.5 Cells/mm^3
Standard Deviation 1038
Mean CD4 Count
CD4 Count after second exposure to intervention
418 Cells/mm^3
Standard Deviation 944
Mean CD4 Count
CD4 Count after third exposure to intervention
390.5 Cells/mm^3
Standard Deviation 834

PRIMARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

Mean viral load at each time point

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean Viral Load
Baseline/exposure 1
97,266 copies/mL
Standard Deviation 340,644
Mean Viral Load
Exposure 2
93,242 copies/mL
Standard Deviation 286,207
Mean Viral Load
Exposure 3
21,116 copies/mL
Standard Deviation 79,176

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

14 questions pertaining to HIV-related knowledge were developed according to the information that will be included in the intervention. Participants will receive one point for each correct answer and then the scores for each question will be summed to obtain a final score. Therefore, the minimum score will be 0 and maximum score will be 14 where the scores closer to 14 indicate patients have more HIV-related knowledge.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean Score on HIV-related Knowledge Assessment
Baseline/exposure 1
10.10 score on a scale
Standard Deviation 2.43
Mean Score on HIV-related Knowledge Assessment
Exposure 2
12.23 score on a scale
Standard Deviation 1.51
Mean Score on HIV-related Knowledge Assessment
Exposure 3
12.21 score on a scale
Standard Deviation 1.59

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

7 questions on patients' satisfaction with health care provider and the health care center adapted from previously validated instruments were included. Each question response from included questions has a different score range: Question 1: 1 - 7 Question 2: 1 - 10 Question 3: 1 - 7 Question 4: 1 - 5 Question 5: 1 - 7 Question 6: 1 - 7 Question 7: 1 - 5 Total scores range from 7 - 48, which is calculated from the lowest and highest possible scores on each of the included questions. Higher scores indicating more satisfaction with care.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean Score on Satisfaction With Care Scale
Baseline/exposure 1
44.93 score on a scale
Standard Deviation 3.40
Mean Score on Satisfaction With Care Scale
Exposure 2
45.18 score on a scale
Standard Deviation 2.81
Mean Score on Satisfaction With Care Scale
Exposure 3
44.29 score on a scale
Standard Deviation 5.06

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

The Self-Efficacy for Managing Chronic Disease (SEMCD) scale is a 6-item questionnaire that measures confidence in one's ability to manage fatigue, pain, emotional distress, and other symptoms using self-management techniques. Each item is scored from a minimum value of 1 which indicates "not at all confident" to a maximum score of 10, which indicates "completely confident." Final scores are calculated as the mean of the 6 questions ranging from 1(minimum) to 10 (maximum), where higher scores indicate higher self-efficacy (better outcome).

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean Score on the SEMCD Scale
Baseline/exposure 1
8.01 score on a scale
Standard Deviation 1.72
Mean Score on the SEMCD Scale
Exposure 2
8.13 score on a scale
Standard Deviation 1.46
Mean Score on the SEMCD Scale
Exposure 3
8.48 score on a scale
Standard Deviation 1.89

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

Adherence will be measured with the validated simplified medication adherence questionnaire (SMAQ)-6 scale, a 6-item questionnaire. A person is considered "non-adherent" if there is a "yes" answer for any of items 1,2,3, and 5. Additionally, if they answer that they have missed more than two doses of their medication in the past week (item 4) or if they have gone more than two days without taking their medication in the past 3 months (item 6), they are also considered "non-adherent."

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Number of Participants Who Are Adherent to Their Medications
Baseline/exposure 1 · Adherent
10 Participants
Number of Participants Who Are Adherent to Their Medications
Baseline/exposure 1 · Non-adherent
20 Participants
Number of Participants Who Are Adherent to Their Medications
Baseline/exposure 1 · Missing
0 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 2 · Adherent
7 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 2 · Non-adherent
15 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 2 · Missing
8 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 3 · Adherent
11 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 3 · Non-adherent
13 Participants
Number of Participants Who Are Adherent to Their Medications
Exposure 3 · Missing
6 Participants

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

Participants rated their general health as "excellent," "very good," "good," "more or less," or "bad."

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · Bad
1 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · More or less
15 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · Good
6 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · Very Good
4 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · Excellent
4 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Baseline/exposure 1 · Missing
0 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · Bad
0 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · More or less
10 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · Good
7 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · Very Good
1 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · Excellent
4 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 2 · Missing
8 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · Bad
0 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · More or less
11 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · Good
5 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · Very Good
4 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · Excellent
4 Participants
Number of Participants Who Reported Each of the 5 General Health Categories
Exposure 3 · Missing
6 Participants

SECONDARY outcome

Timeframe: Baseline, 3-, and 6-months

Population: 2 participants were withdrawn from the study by the PI, therefore, 30 subjects were included in the analysis.

Current health status will be assessed with one question from the Health Status Assessment which asks participants to rate their current health by providing a number on a scale from 0 - 100 where 0=death or worst possible health and 100=perfect or best possible health.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Mean Score on Current Health Status
Baseline/exposure 1
68 score on a scale
Standard Deviation 20.66
Mean Score on Current Health Status
Exposure 2
75.45 score on a scale
Standard Deviation 17.03
Mean Score on Current Health Status
Exposure 3
82.29 score on a scale
Standard Deviation 16.8

SECONDARY outcome

Timeframe: Baseline visit only

Population: 2 participants were withdrawn from the study by the PI and, therefore, their data are not included in the analysis.

Health literacy will be assessed using the short assessment of health literacy- Spanish. Scores range from 0 - 18 and a score above a 15 indicates that participants are likely to have adequate health literacy.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Number of Participants With Likely Low vs. Adequate Health Literacy According to SAHL-S&E Measurement
Missing
1 Participants
Number of Participants With Likely Low vs. Adequate Health Literacy According to SAHL-S&E Measurement
Likely adequate health literacy
16 Participants
Number of Participants With Likely Low vs. Adequate Health Literacy According to SAHL-S&E Measurement
Likely low health literacy
13 Participants

SECONDARY outcome

Timeframe: Baseline visit only

Population: 2 participants were withdrawn from the study by the PI and, therefore, their data are not included in analyses.

A second measure of health literacy, the Newest Vital Sign (NVS) will also be administered. Scores on this scale range from 0-6 where a score of 0-1 suggests high likelihood of limited literacy, a score of 2-3 indicates the possibility of limited literacy, and a score of 4-6 almost always indicates adequate literacy.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Number of Participants With Likely Limited, Possibly Limited, or Adequate Health Literacy According to NVS Measurement
Likely adequate health literacy
5 Participants
Number of Participants With Likely Limited, Possibly Limited, or Adequate Health Literacy According to NVS Measurement
Possibility of limited health literacy
11 Participants
Number of Participants With Likely Limited, Possibly Limited, or Adequate Health Literacy According to NVS Measurement
Likely limited health literacy
14 Participants

SECONDARY outcome

Timeframe: Baseline visit only

Population: 2 participants were withdrawn from the study by the PI and, therefore, were not included in analyses

The Brief Acculturation Rating Scale for Mexican Americans-II (Brief ARSMA)12 item instrument that assesses level of acculturation that has been used in Mexican Americans as well as other Latino subgroups, including Dominicans. Scores are calculated by summing the scores and dividing by 12 to get a mean acculturation. Higher scores indicate greater acculturation.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Number of Participants in Each Acculturation Category Presented in the Brief ARSMA
Very oriented to original culture
13 Participants
Number of Participants in Each Acculturation Category Presented in the Brief ARSMA
Oriented to original culture to approximately balanced bicultural
6 Participants
Number of Participants in Each Acculturation Category Presented in the Brief ARSMA
Slightly Anglo oriented bicultural
4 Participants
Number of Participants in Each Acculturation Category Presented in the Brief ARSMA
Strongly Anglo oriented
4 Participants
Number of Participants in Each Acculturation Category Presented in the Brief ARSMA
Very assimilated
3 Participants

SECONDARY outcome

Timeframe: 6 months after baseline

Population: 2 participants were withdrawn from the study by the PI and, therefore, they are not included in analyses.

Participants will be invited to participate in an in-depth qualitative interview regarding their experiences. The number who participate will be reported as a percent of the total who are enrolled.

Outcome measures

Outcome measures
Measure
Infographic Intervention Group
n=30 Participants
Participants in the intervention group will receive health education using infographics (Infographic Intervention) during a study visit scheduled immediately following their regularly scheduled clinic visits. Infographic intervention: Information visualizations (infographics) will be used to teach participants about HIV during study visits immediately following their normal clinic visits.
Percent of Participants Who Complete an In-depth Qualitative Interview
24 Participants

Adverse Events

Intervention Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Samantha Stonbraker

University of Colorado College of Nursing

Phone: 3037248281

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place