A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Italy, as Part of Local Clinical Practice

NCT ID: NCT04094415

Last Updated: 2023-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

581 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-28

Study Completion Date

2021-07-28

Brief Summary

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The purpose of the study is to collect information on how semaglutide works in real world patients. Participants will get semaglutide prescribed to them by their doctor. The study will last for about 6 to 8 months. Participants will be asked to complete some questionnaires about their health and your diabetes treatment. Participants will complete these during their normally scheduled visits with their doctor.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 2

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Semaglutide

Participants will receive semaglutide at the treating physician's discretion as part of the usual clinical practice. The prescription and use of semaglutide is completely independent of this study. Total study duration for the individual patient will be approximately 30 weeks.

Semaglutide

Intervention Type DRUG

Patients will be treated with commercially available semaglutide in a prefilled pen injector (FlexTouch® variant) according to routine local clinical practice at the discretion of the treating physician. Other anti-hyperglycaemic treatments will be prescribed at the physician's discretion.The decision to initiate treatment with semaglutide is at the treating physician's discretion, and clearly separated from the decision to include the patient in the study.

Interventions

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Semaglutide

Patients will be treated with commercially available semaglutide in a prefilled pen injector (FlexTouch® variant) according to routine local clinical practice at the discretion of the treating physician. Other anti-hyperglycaemic treatments will be prescribed at the physician's discretion.The decision to initiate treatment with semaglutide is at the treating physician's discretion, and clearly separated from the decision to include the patient in the study.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Signed informed consent obtained before any study-related activities (study-related activities are any procedures related to recording of data according to protocol)
* The decision to initiate treatment with commercially available semaglutide has been made by the patient/Legally Acceptable Representative and the treating physician before and independently from the decision to include the patient in this study
* Male or female, age 18 years or older at the time of signing informed consent
* Diagnosed with type 2 diabetes at least 12 weeks prior to inclusion
* Available and documented haemoglobin A1c (HbA1c) value equal to or less than 12 weeks prior to initiation of semaglutide treatment

Exclusion Criteria

* Previous participation in this study. Participation is defined as having given informed consent in this study
* Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation
* Treatment with any investigational drug within 90 days prior to enrolment into the study
* Hypersensitivity to semaglutide or to any of the excipients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Reporting Anchor and Disclosure (1452)

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Novo Nordisk Investigational Site

Bagno a Ripoli, , Italy

Site Status

Novo Nordisk Investigational Site

Bari, , Italy

Site Status

Novo Nordisk Investigational Site

Bergamo, , Italy

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Novo Nordisk Investigational Site

Bergamo, , Italy

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Novo Nordisk Investigational Site

Bologna, , Italy

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Novo Nordisk Investigational Site

Brindisi, , Italy

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Novo Nordisk Investigational Site

Casarano (Lecce), , Italy

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Novo Nordisk Investigational Site

Catanzaro, , Italy

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Novo Nordisk Investigational Site

Chieri Torino, , Italy

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Novo Nordisk Investigational Site

Cipolleto Perugia, , Italy

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Novo Nordisk Investigational Site

Foggia, , Italy

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Novo Nordisk Investigational Site

Gaeta, , Italy

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Novo Nordisk Investigational Site

Genova, , Italy

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Novo Nordisk Investigational Site

Livorno, , Italy

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Novo Nordisk Investigational Site

L’Aquila, , Italy

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Novo Nordisk Investigational Site

Macerata, , Italy

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Novo Nordisk Investigational Site

Milan, , Italy

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Novo Nordisk Investigational Site

Milan, , Italy

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Novo Nordisk Investigational Site

Milan, , Italy

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Novo Nordisk Investigational Site

Napoli, , Italy

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Novo Nordisk Investigational Site

Napoli, , Italy

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Novo Nordisk Investigational Site

Napoli, , Italy

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Novo Nordisk Investigational Site

Napoli, , Italy

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Novo Nordisk Investigational Site

Negrar (VR), , Italy

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Novo Nordisk Investigational Site

Orbassano, , Italy

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Novo Nordisk Investigational Site

Pavia, , Italy

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Novo Nordisk Investigational Site

Prato, , Italy

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Novo Nordisk Investigational Site

Ravenna, , Italy

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Novo Nordisk Investigational Site

Roma, , Italy

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Novo Nordisk Investigational Site

Roma, , Italy

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Novo Nordisk Investigational Site

Rome, , Italy

Site Status

Novo Nordisk Investigational Site

Rozzano (MI), , Italy

Site Status

Novo Nordisk Investigational Site

Sesto San Giovanni (MI), , Italy

Site Status

Novo Nordisk Investigational Site

Treviglio (Bergamo), , Italy

Site Status

Novo Nordisk Investigational Site

Treviso, , Italy

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Novo Nordisk Investigational Site

Udine, , Italy

Site Status

Novo Nordisk Investigational Site

Vicenza, , Italy

Site Status

Novo Nordisk Investigational Site

Vicenza, , Italy

Site Status

Novo Nordisk Investigational Site

Vigevano, , Italy

Site Status

Countries

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Italy

References

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Napoli R, Berra C, Catarig AM, Di Loreto C, Donatiello E, Berentzen TL, Pitocco D, Giorgino F. Once-weekly semaglutide use in patients with type 2 diabetes: Real-world data from the SURE Italy observational study. Diabetes Obes Metab. 2023 Jun;25(6):1658-1667. doi: 10.1111/dom.15020. Epub 2023 Mar 12.

Reference Type BACKGROUND
PMID: 36789682 (View on PubMed)

Other Identifiers

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U1111-1233-2023

Identifier Type: OTHER

Identifier Source: secondary_id

NN9535-4549

Identifier Type: -

Identifier Source: org_study_id

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