Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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SUSPENDED
40 participants
OBSERVATIONAL
2019-08-19
2028-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Young
Observational study without intervention
Observational study without intervention
Observational study without intervention
Elderly
Observational study without intervention
Observational study without intervention
Observational study without intervention
Interventions
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Observational study without intervention
Observational study without intervention
Eligibility Criteria
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Inclusion Criteria
* cardiovascular risk prevention, intake of low dose aspirin,
* hypertension, intake of beta-blockers, ACE inhibitors, diuretics, calcium channel blockers
* hypercholesterinemia, intake of statins
* Cases: 70-85 years of age
* Controls: 20-35 years of age
* Patients must be able to read and understand English
* Participants must sign the informed consent form
* Participants must have a wrist-actigraphy-based average TST (total sleep time) ≥ 6 hours per night (measured over 7 consecutive days) occurring between 22:00 - 08:00
Exclusion Criteria
* Shift work, defined as recurring work between 22:00-05:00
* History of clinically significant obstructive sleep apnea
* Transmeridian travel across ≥2 time zones in the two weeks prior to the blood draws and one week after,
* \> 2 drinks of alcohol per day
* Use of illicit drugs
20 Years
85 Years
ALL
Yes
Sponsors
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University of Pennsylvania
OTHER
Responsible Party
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Principal Investigators
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Carsten Skarke, MD
Role: PRINCIPAL_INVESTIGATOR
University of Pennsylvania
Locations
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University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania, United States
Countries
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Other Identifiers
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832866
Identifier Type: -
Identifier Source: org_study_id
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