The Effect of CPAP on Lung Hyperinflation in Patients With OSA
NCT ID: NCT04084899
Last Updated: 2020-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
50 participants
OBSERVATIONAL
2019-09-05
2020-01-09
Brief Summary
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Detailed Description
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Obstructive sleep apnoea (OSA) is characterized by repetitive closure of upper airways leading to apnoea (complete airflow cessation) or hypopnoea (airflow limitation \> 50% + blood oxygen desaturation \> 3% or airflow limitation \> 30% blood oxygen desaturation \> 4%). The prevalence of lung hyperinflations in sleep apnoea patients and effect of continuous positive airway pressure (CPAP) therapy is not known.
Process:
Subjects included in the study will be obstructive sleep apnoea (OSA) patients diagnosed by respiratory polysomnography performed in the Sleep Laboratory, Department of Respiratory Medicine, University Hospital Olomouc.
Bodypletysmography will be performed in the time of OSA diagnosis and after 3 months of CPAP therapy.
Data will be statistically evaluated after completion of the target number of subjects.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Continuous Positive Airway Pressure
Patient treated with continuous positive airway pressure
Continuous Positive Airway Pressure therapy
Standard treatment with continuous positive airway pressure
Interventions
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Continuous Positive Airway Pressure therapy
Standard treatment with continuous positive airway pressure
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Total lung capacity \< 80% lower limit of normal values
* Obstructive ventilatory disorder
* Change in body weight ˃ 10%
* Change in smoking status
18 Years
ALL
No
Sponsors
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University Hospital Olomouc
OTHER
Responsible Party
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Milan Sova
Principal Investigator, Head of Sleep Laboratory, Department of Respiratory Medicine
Principal Investigators
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Milan Sova, MD, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Department of Respiratory Medicine, University Hospital Olomouc
Locations
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University Hospital Olomouc
Olomouc, , Czechia
Countries
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Other Identifiers
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OSAS_bodypletysmo
Identifier Type: -
Identifier Source: org_study_id
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