Phonoaudiologic Therapy Adjunct to Treatment on Patients With Obstructive Sleep Apnea

NCT ID: NCT01289405

Last Updated: 2014-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Brief Summary

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Objective: to evaluate the effects of a speech therapy exercises program in the treatment of Obstructive Sleep Apna Syndrome (OSAS) patients based on the clinical and polysomnography (PSG) parameters.

Methods: 80 patients with OSAS will be evaluated: men, 25-65 years old, body mass index \< 35 kg/m2 and scores of Epworth Sleepiness Scale \> 9. Patients will be divided into four groups: I: 20 patients with OSAS underwent speech therapy; II: 20 patients with OSAS underwent placebo therapy of Speech Therapy; III: 20 patients starting treatment with CPAP underwent speech therapy; IV: 20 patients starting treatment with CPAP without speech therapy or placebo. The speech therapy include isometric and isotonic exercises to improve posture, mobility and muscle tone of the soft palate, pharyngeal constrictor muscles, tip and base of tongue, cheeks and lips. Placebo therapy includes relaxation exercises and stretching neck, without therapeutic purpose. Both therapies are applied for three months, three times a day, lasting 20 minutes each session. During the treatment, the subjects will be monitored in weekly meetings, for orientation and description of the exercises and return of the fulfilled exercises diary. The subjects will also be followed at the CPAP clinic in returns after one week, a month and at the end of the study. Conduct assessments before and after treatment and after twenty one days washout, including: assessing the upper airway, anthropometric investigation of the facial skeleton and speech of Orofacial, questionnaires (Epworth Sleepiness Scale, FOSQ, General Segment and use of CPAP, WHOQOL-BREF, snoring), Psychomotor Vigilance Test and PSG.

Detailed Description

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Conditions

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Obstructive Sleep Apnea Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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placebo exercices

relaxation exercises and stretching neck, without therapeutic purpose.

Group Type PLACEBO_COMPARATOR

Continuous Positive Airway Pressure (CPAP)

Intervention Type DEVICE

mechanical splint to open airway during sleep, considered the gold standard treatment for patients with obstructive sleep apnea

phonoaudiologic therapy

isometric and isotonic exercises to improve posture, mobility and muscle tone of the soft palate, pharyngeal constrictor muscles, tip and base of tongue, cheeks and lips.

Group Type ACTIVE_COMPARATOR

Continuous Positive Airway Pressure (CPAP)

Intervention Type DEVICE

mechanical splint to open airway during sleep, considered the gold standard treatment for patients with obstructive sleep apnea

Interventions

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Continuous Positive Airway Pressure (CPAP)

mechanical splint to open airway during sleep, considered the gold standard treatment for patients with obstructive sleep apnea

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with a recent diagnosis of OSAS
* Body mass index (BMI) \< 35 kg/m2

Exclusion Criteria

* Facial malformations
* Regular use of hypnotic medications
* Hypothyroidism
* Previous stroke
* Neuromuscular disease
* Heart failure
* Coronary disease
* Severe obstructive nasal disease
Minimum Eligible Age

25 Years

Maximum Eligible Age

65 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Associação Fundo de Incentivo à Pesquisa

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. Lia Azeredo-Bittencourt

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lia Rita A Bittencourt, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidade Federal de São Paulo

Locations

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Associação Fundo de Incentivo a Psicofarmacologia

São Paulo, São Paulo, Brazil

Site Status

Countries

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Brazil

References

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Diaferia G, Santos-Silva R, Truksinas E, Haddad FLM, Santos R, Bommarito S, Gregorio LC, Tufik S, Bittencourt L. Myofunctional therapy improves adherence to continuous positive airway pressure treatment. Sleep Breath. 2017 May;21(2):387-395. doi: 10.1007/s11325-016-1429-6. Epub 2016 Dec 2.

Reference Type DERIVED
PMID: 27913971 (View on PubMed)

Other Identifiers

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CEP 2002/08

Identifier Type: -

Identifier Source: org_study_id

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