Remote Ischemic Preconditioning During Lower Limb Revascularization
NCT ID: NCT04016857
Last Updated: 2021-10-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2018-01-15
2019-06-15
Brief Summary
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Remote ischemic preconditioning(RIPC) is a simple, cost-free and non invasive procedure (transient upper limb ischemia/reperfusion) that could provide organ protection (Heart, Brain and Kidney) following ischemia injuries.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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RIPC Group
Remote ischemic preconditioning
RIPC
4 cycles of 5-min inflation to 200 mmHg followed by 5-min deflation of arm cuff
Control Group
Sham remote ischemic preconditioning
Control
deflated cuff placed on the left arm for 40 min
Interventions
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RIPC
4 cycles of 5-min inflation to 200 mmHg followed by 5-min deflation of arm cuff
Control
deflated cuff placed on the left arm for 40 min
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Chronic kidney disease in stage 4 or 5 (eGFR\<30 ml/min/1,73m2)
* Patients underwent contrast-enhanced radiological exams in the previous 7 days
* Treatment with glibencamide or prostaglandins
18 Years
ALL
No
Sponsors
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University of Messina
OTHER
Responsible Party
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Alberto Noto
Professor of Anaesthesia
Principal Investigators
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Alberto Noto, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Messina
Locations
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A.O.U. G.Martino - University of Messina
Messina, , Italy
Countries
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Other Identifiers
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UMEANE1
Identifier Type: -
Identifier Source: org_study_id
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