Raman Spectroscopy and Endometriosis

NCT ID: NCT04015297

Last Updated: 2019-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2020-09-01

Brief Summary

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We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.

Detailed Description

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Endometriosis is a chronic disease whose molecular basis is still unknown and diagnostic methods are controversial. The diagnosis is still invasive and there are no accepted ways which are molecular-based and noninvasive. Raman spectroscopy is a vibrational spectroscopy technique which can analyze specific spectral patterns, substances and molecular changes with high specificity. We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.

Conditions

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Endometriosis Endometrioma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Investigators

Study Groups

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control

healthy controls

Group Type EXPERIMENTAL

raman analysis

Intervention Type DIAGNOSTIC_TEST

negative or pozitive

patient

patients diagnosed with endometriosis

Group Type EXPERIMENTAL

raman analysis

Intervention Type DIAGNOSTIC_TEST

negative or pozitive

Interventions

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raman analysis

negative or pozitive

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* proven endometriosis

Exclusion Criteria

* having additional health conditions
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Acibadem University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bahar Yuksel, md

Role: STUDY_DIRECTOR

esenler maternity and children's hospital

Locations

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Bahar Yuksel

Istanbul, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Bahar Yuksel

Role: CONTACT

05424732003

Facility Contacts

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Bahar Yuksel

Role: primary

5424732003

References

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Lyng FM, Traynor D, Ramos IR, Bonnier F, Byrne HJ. Raman spectroscopy for screening and diagnosis of cervical cancer. Anal Bioanal Chem. 2015 Nov;407(27):8279-89. doi: 10.1007/s00216-015-8946-1. Epub 2015 Aug 16.

Reference Type BACKGROUND
PMID: 26277185 (View on PubMed)

Eberhardt K, Stiebing C, Matthaus C, Schmitt M, Popp J. Advantages and limitations of Raman spectroscopy for molecular diagnostics: an update. Expert Rev Mol Diagn. 2015 Jun;15(6):773-87. doi: 10.1586/14737159.2015.1036744. Epub 2015 Apr 15.

Reference Type BACKGROUND
PMID: 25872466 (View on PubMed)

Other Identifiers

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ob&gyn raman

Identifier Type: -

Identifier Source: org_study_id

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