Systemic Inflammatory Indices as a Non-invasive Grading Modality for Endometriosis

NCT ID: NCT06298617

Last Updated: 2024-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

88 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-12-25

Brief Summary

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Endometriosis (EMs) is one of the commonest chronic inflammatory disorder affecting women and is characterized by the presence and growth of endometrial-like glandular epithelial and stromal cells outside the uterus leading to multiple clinical symptoms affecting patients quality of life and fertility with high recurrence rate . The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are documented as prognostic serum biomarker in many kinds of cancer and for the need and outcomes of adjuvant therapies for various cancers .

Detailed Description

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Conditions

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Endometriosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Study group

Diagnostic laparoscopy

Intervention Type PROCEDURE

All women will undergo exploratory laparoscopy under general anesthesia

Full Blood Count (FBC)

Intervention Type DIAGNOSTIC_TEST

Blood samples withdrawn from patients on EDITA tubes and gone through full blood count and differential leucocytic count

Interventions

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Diagnostic laparoscopy

All women will undergo exploratory laparoscopy under general anesthesia

Intervention Type PROCEDURE

Full Blood Count (FBC)

Blood samples withdrawn from patients on EDITA tubes and gone through full blood count and differential leucocytic count

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Women with clinical manifestations suggestive of having EM;
* Women who was professionally diagnosed;
* Women who was diagnosed by radiologic workup;

Exclusion Criteria

* Women with EM and were maintained on treatment or underwent operative interference during the last three months;
* Patients had autoimmune diseases, maintained on immunosuppressive therapy for any indication;
* Women with cancer elsewhere in the body or receiving adjuvant therapies for cancer;
* Patients receiving therapies for viral disorders especially COVID;
* Patients refusing to undergo the exploratory laparoscopy.
Minimum Eligible Age

25 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Sabra

Lecturer of Obstetrics & Gynecology Department, Faculty of Medicine.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Benha University

Banhā, Al Qalyobia, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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RC 27.1.2024

Identifier Type: -

Identifier Source: org_study_id

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