Pharmaceutical Intervention and Adherence to bDMARDs in Spondyloarthritis.

NCT ID: NCT04001673

Last Updated: 2020-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-02-15

Study Completion Date

2018-09-15

Brief Summary

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There is a lack of knowledge among patients concerning their treatment with bDMARDs, which could lead to low adherence.

The objective of this study is to assess the impact of a pharmacist's intervention on the adherence to bDMARDs in patients with Spondyloarthritis.

Detailed Description

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This is an interventional, controlled, open-label and monocentric study. 80 patients are planned to be included.

After written informed consent will be obtained, the patients will be randomized in two arms:

* Intervention arm: intervention of a pharmacist who will explain bDMARDs management.
* Control arm, without intervention.

Two primary end-points are defined:

1. the changes from baseline to M6 in the patients' knowledge score about subcutaneous bDMARD management
2. the changes from baseline to M6 in Medication Possession Ratio (MPR)

As secondary end-points, the changes in disease activity and patients' satisfaction regarding the pharmacists' intervention are evaluated.

Conditions

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Spondyloarthritis Treatment Adherence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Pharmacist's intervention

Evaluation of knowledge and adherence of patients treated by bDMARDs before and after the intervention of a pharmacist that will give information concerning bDMARDs management.

Group Type ACTIVE_COMPARATOR

Pharmacist's intervention

Intervention Type BEHAVIORAL

Information about bDMARDs management.

Control

Evaluation of knowledge and adherence of patients treated by bDMARDs who did not receive pharmacist's intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Pharmacist's intervention

Information about bDMARDs management.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Outpatients from Rheumatology Department at Cochin Hospital
* Diagnosis of Spondyloarthritis
* Under treatment with subcutaneous bDMARDs for at least 6 months
* Disease activity stable for at least 6 months
* No treatment modification 3 months before or after inclusion in the study
* Informed consent signed and dated
* Older than 18 years
* Patients who speak french

Exclusion Criteria

* Patients who have had a change in the treatment of SpA during the 3 months prior or after the inclusion
* History of psychological problems
* Patients who need other persons to manage their treatment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dr Ornella Conort

OTHER

Sponsor Role lead

Responsible Party

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Dr Ornella Conort

Pharmacist

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Hôpital Cochin

Paris, Ille de France, France

Site Status

Countries

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France

Other Identifiers

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2016-A01897-44

Identifier Type: -

Identifier Source: org_study_id

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