Translating Neuroscience to Population Health

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-24

Study Completion Date

2019-07-11

Brief Summary

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The current study will examine the relationship between brain responses and a guided imagery exercise in overweight and obese individuals. Results of this work are highly relevant to public health because they employ neuroimaging methods to understand food decision-making. Findings from this study will inform health decision making and holds great potential for future translation across multiple health behaviors and scalable interventions to impact population health

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Detailed Description

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Negative health behaviors (e.g. overeating, smoking) are associated with increased negative health outcomes. Engaging in healthy behaviors is not always rewarding (e.g. carrot vs. cake). Neural models of healthy behaviors focus on the balance between reward and regulation brain regions. The current pilot application examines the engagement of these regions during the evaluation of food and nonfood cues before and after a guided imagery exercise targeting positive associations with food and regulation.

The long-term goal is to understand the interaction between positive associations with healthy foods and thinking about future rewards may influence healthy decision-making. The objective of the current study is to empirically test the combined effects of positive affect and positive episodic future thinking on brain activation.

Conditions

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Overweight and Obesity

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Participants will be assigned to a guided imagery exercise

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Guided Imagery

Participants will listen to a guided imagery recording

Group Type EXPERIMENTAL

Guided Imagery

Intervention Type BEHAVIORAL

The guided imagery exercise asks participants to think about positive associations with healthy foods and imagine their future healthy selves.

Interventions

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Guided Imagery

The guided imagery exercise asks participants to think about positive associations with healthy foods and imagine their future healthy selves.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* body mass index 25 to 55 kg/m2
* right-handed
* not currently dieting or attempting to lose weight.

Exclusion Criteria

* serious medical illness unsuitable for the magnetic resonance imaging scanner based on best clinical judgment
* any neurologic or current psychiatric diagnosis
* currently taking anti-seizure medication
* history of concussion
* left-handedness
* risk for hazard due to magnetic fields such as metal in the body surgically or accidentally
* pregnancy

Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes