Relationships and Differences Analysis in Heart Failure

NCT ID: NCT03966729

Last Updated: 2022-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-01

Study Completion Date

2023-12-31

Brief Summary

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This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF \< 40%), HFmrEF (EF 40-49%), and HFpEF (EF\>50%), contributing to an improved diagnosis, prognosis and therapy of patients with heart failure.

Detailed Description

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The varying clinical picture of heart failure (HF) represents a major challenge for patient care in Germany. HF is one of the most common reasons for hospitalization in the Western world. In the chronic course of heart failure, affected patients are committed to morbidity, lifelong therapy and high risk of cardiac decompensation, also associated with high mortality.

Heart failure patients, who visited the Cardiology Department of the University Hospital Wuerzburg, shall be analyzed with regard to all clinical data and outcome. This retrospective work should help to better understand the three groups HFrEF (EF \< 40%), HFmrEF (EF 40-49%) and HFpEF (EF\>50%) and help identifying similarities and differences between the groups.

Hereby we hope for progress in diagnostic, prognostic and therapeutic aspects of heart failure.

Conditions

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Heart Failure Chronic Heart Failure Chronic Heart Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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HFrEF

HFrEF (Heart failure with reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF \< 40%.

LVEF = Left ventricular ejection fraction

Time (outcome)

Intervention Type OTHER

HFmrEF

HFmrEF (Heart failure with mid-range reduced ejection fraction): ESC Guideline heart failure 2016: patients with LVEF 40-49%.

LVEF = Left ventricular ejection fraction

Time (outcome)

Intervention Type OTHER

HFpEF

HFmrEF (Heart failure with preserved ejection fraction): ESC Guideline heart failure 2016: patients with LVEF \> 50%.

LVEF = Left ventricular ejection fraction

Time (outcome)

Intervention Type OTHER

Interventions

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Time (outcome)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis: Heart failure
* Minimum of two echocardiographic examinations in a minimum time frame of six months
* Patients must have reached the age of 18
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wuerzburg University Hospital

OTHER

Sponsor Role lead

Responsible Party

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PD Dr. Peter Nordbeck

Head Consultant Cardiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Peter Nordbeck, MD, PhD

Role: STUDY_CHAIR

Wuerzburg University Hospital

Locations

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University Hospital Würzburg

Würzburg, Bavaria, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Peter Nordbeck, MD, PhD

Role: CONTACT

+49 931 201 39181

Kai Hu, MD

Role: CONTACT

+49 931 201 0

Other Identifiers

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REDEAL-HF

Identifier Type: -

Identifier Source: org_study_id

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