Congestive Heart Failure: Causes of Sudden Worsening

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-02-28

Study Completion Date

2012-02-29

Brief Summary

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The purpose of the study is to recognize main causes of acute decompensation of chronic congestive heart failure.

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Detailed Description

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Congestive heart failure (CHF) presents a very significant cause of morbidity and mortality. The prevalence of CHF is between 2 and 4% and rises with age (in 70- to 80-year-old people is between 10 and 20%). CHF is the cause of 5% of all acute hospital admissions and accounts for 2% of expenses on health. The most common causes of worsening of the chronic CHF are ischemia, arrhythmias, valvular dysfunction, systemic or pulmonary hypertension, volume overload or fluid retention, high output conditions (infection, anemia, thyrotoxicosis), drugs (NSAIDs, cyclo-oxygenase (COX) inhibitors, thiazolidinediones) and medication nonadherence. The goal of this study is to determine the proportion of various reasons of acute worsening of CHF, using commonly available methods including assessment of serum drug levels.

Conditions

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Congestive Heart Failure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Congestive heart failure

Patients suffering from sudden worsening of congestive heart failure

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* able to provide informed consent
* aged 19 years or more
* history of heart failure of at least one month
* examined or hospitalized for acute dyspnea at rest or with minimal exertion
* clinical signs of fluid overload defined as at least one of following:
* rales
* jugular venous distension
* peripheral edema
* pulmonary congestion on X-ray
* NT-proBNP above 210 pmo/l