Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP

NCT ID: NCT03963791

Last Updated: 2019-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-05

Study Completion Date

2020-06-01

Brief Summary

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This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.

Detailed Description

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Conditions

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Dental Caries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Eggshell powder gel

prepared from eggshell powder. applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.

Group Type EXPERIMENTAL

Eggshell powder gel

Intervention Type OTHER

Eggshell powder gel produced from chicken eggs.

CPP-ACP crème

Intervention Type OTHER

A water-based, sugar-free topical cream containing Recaladent (CCP-ACP) which is derived from the milk protein.

CPP-ACP crème

CPP-ACP crème (GC Tooth Mousse). applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.

Group Type ACTIVE_COMPARATOR

Eggshell powder gel

Intervention Type OTHER

Eggshell powder gel produced from chicken eggs.

CPP-ACP crème

Intervention Type OTHER

A water-based, sugar-free topical cream containing Recaladent (CCP-ACP) which is derived from the milk protein.

Interventions

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Eggshell powder gel

Eggshell powder gel produced from chicken eggs.

Intervention Type OTHER

CPP-ACP crème

A water-based, sugar-free topical cream containing Recaladent (CCP-ACP) which is derived from the milk protein.

Intervention Type OTHER

Other Intervention Names

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Natural product MI Paste

Eligibility Criteria

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Inclusion Criteria

* A patient who has just completed a comprehensive orthodontic treatment.
* Presence of at least one WSL, DIAGNOdent score (0-20).
* Age range between 13 and 35years.

Exclusion Criteria

* Patients are unable to return for recall appointments.
* High caries risk.
* Have plaque accumulation and a periodontal problem
* In progress treatment of chronic disease.
* Presence of abnormal oral, medical, or mental condition (including any milk-related allergies or any medical condition involving kidneys or salivary glands).
* Presence of dentin caries, enamel hypoplasia or restorations on maxillary anterior teeth.
Minimum Eligible Age

13 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mohammad A Sarhan

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cairo univercity

Cairo, , Egypt

Site Status

Countries

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Egypt

Facility Contacts

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Mohammad Sarhan, BDS

Role: primary

+201005531301

Other Identifiers

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Oper_607

Identifier Type: -

Identifier Source: org_study_id

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