Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery

NCT ID: NCT03958435

Last Updated: 2021-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-11-09

Study Completion Date

2023-12-15

Brief Summary

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Background:

1. . The incidence and mortality of colon cancer are high in China and in the world.
2. . The treatment of many patients in the real world is not standardized, and there are problems such as over-treatment or under-treatment. To explore the adjuvant treatment of colon cancer in the Chinese population, this study will retrospectively analyze real-world data on adjuvant therapy for colon cancer in Chinese patients after radical surgery.

The purpose of research:

1. . Current status of adjuvant therapy for stage II-III colon cancer in the real world: chemotherapy regimen, chemotherapy time, efficacy, safety, etc.
2. . Comparison of efficacy and safety of different adjuvant chemotherapy time (\<3 months vs. \>=3 months) in high-risk stage II and III colon cancer patients in the real world
3. . Comparison of efficacy and safety of different adjuvant chemotherapy regimens (XELOX vs. FOLFOX) in high-risk stage II and III colon cancer patients in the real world

Detailed Description

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Conditions

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Stage II Colon Cancer Stage III Colon Cancer Adjuvant Therapy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients who are sick after January 2010
* Age is older than 18
* Surgical pathology confirmed TNM stage II-III (AJCC 7th edition) colon cancer

Exclusion Criteria

* Combine other tumors
* Pathological information is not clear
* Researchers believe that other reasons are not suitable for enrollment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Jiangsu Province People Hospital

Nanjing, Jiangsu, China

Site Status RECRUITING

Changhai Hospital of Shanghai

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

SAHZU

Hangzhou, Zhejinag, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ying Yuan, Ph.D&MD

Role: CONTACT

+86-571-87784795

Facility Contacts

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Yanhong Gu, MD

Role: primary

Wei Zhang, MD

Role: primary

Ying Yuan, Ph.D & MD

Role: primary

Ying Yuan

Role: backup

Other Identifiers

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REDUCE201809

Identifier Type: -

Identifier Source: org_study_id

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