Intranasal Fentanyl for the Treatment of Acute Severe Pain on the Pediatric Emergency Department of Mercy Hospital.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

83 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-30

Study Completion Date

2019-05-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The treatment of acute severe pain in pediatric emergencies required a quick and effective therapeutic support. Actually in France, only peripheral venous access or oral therapies with onset of action are commonly used and only few treatments can be used to manage the acute severe pain in children. In June 2017, an intranasal fentanyl use protocol has been established in the pediatric emergency department of Mercy hospital-Metz. The intranasal fentanyl treatment has proved his effectiveness and safe condition in many countries since few years even though has not yet obtained a marketing authorization for use in children in France. In view of the information, parental permission was obtained before the intranasal administration. The efficacy and surveillance data in all patient records of children who benefited this analgesic protocol were retrospectively collected between June 2017 and August 2018. This retrospective study wants to describe the efficacy and safety of intranasal fentanyl on the pediatric emergency department.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluation of the "Intranasal Fentanyl" Protocol in Pediatric Surgical Emergencies at Strasbourg University Hospital

NCT06832046

Musculoskeletal Pain

RECRUITING

Intranasal Fentanyl Versus Oral Morphine Sulfate in the Treatment of Pain in Pediatric Trauma

NCT03063359

Pain, Acute

TERMINATED PHASE3

Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine

NCT06464146

Limb Injury

RECRUITING PHASE3

Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children

NCT01549002

Abscess Pain

COMPLETED PHASE3

Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.

NCT06968546

Traumatology Wounds and Injury Fractures Bone +4 more

NOT_YET_RECRUITING PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All patients who received fentanyl intranasal between june 2017 and august 2018

Exclusion Criteria

* Lack of surveillance data in the medical record of the patient

Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

CHR Metz Thionville

Metz, Moselle, France

Site Status

Countries

Review the countries where the study has at least one active or historical site.

France

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2018-07Obs-CHRMT

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Pain Reduction With Intranasal Medications for Extremity Injuries

NCT02778880 COMPLETED PHASE3

Alfentanil Versus Sufentanil for Pain in Children During for Tracheal Suction

NCT01235637 COMPLETED PHASE3

Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Participants

NCT02395653 COMPLETED PHASE3

IN Sub-Dissociative Ketamine vs IN Fentanyl

NCT02521415 COMPLETED PHASE2

RCT Evaluating Intranasal Fentanyl in the Pain Management of Children With Headaches

NCT02638506 TERMINATED PHASE4

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

NCT01951963 COMPLETED PHASE4

Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Opioid Tolerant Pediatric Subjects

NCT01206907 WITHDRAWN PHASE3

Pediatric Ketamine Study for Pain Management

NCT02388321 TERMINATED PHASE4

Pharmacokinetics of Intravenous Metamizole in Children Less Than 6 Years Old

NCT02660177 COMPLETED PHASE2

Methoxyflurane Analgesia for Paediatric Injuries

NCT03215056 COMPLETED PHASE3

Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.

NCT02437669 COMPLETED PHASE2

Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED

NCT04150757 TERMINATED PHASE3

Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers

NCT02434939 COMPLETED PHASE4

Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

NCT03950817 COMPLETED PHASE4

A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients

NCT01635101 COMPLETED PHASE3

Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain

NCT00595530 TERMINATED PHASE2

Nasal Administration of Sufentanil+Ketamine for Procedure-related Pain in Children

NCT01047241 COMPLETED PHASE2

Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine

NCT00224692 TERMINATED PHASE3

Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia

NCT02481791 UNKNOWN PHASE3

Intranasal Ketamine and Fracture Reduction in Pediatric Emergencies (KETAPED)

NCT03525821 COMPLETED PHASE3

Intranasal Ketamine Effectiveness in Reducing Intramuscular Injection Pain Before Sedation Among Children

NCT06139380 COMPLETED PHASE4

Pharmacokinetic Study of Intranasal CT001 in Children 1-17 Years of Age Undergoing Elective Surgical Procedures

NCT04897750 COMPLETED PHASE2

Remifentanil in Children With Obstructive Sleep Apnea

NCT03958396 COMPLETED EARLY_PHASE1

Critical Respiratory Events in Children Requiring Naloxone: Naloxone Use as Opioid Safety Measure

NCT01860885 COMPLETED

Morphine or Ketamine for Analgesia

NCT06835504 NOT_YET_RECRUITING PHASE3