Bloodstream Infections in Patients With Rheumatoid Arthritis

NCT ID: NCT03908086

Last Updated: 2019-04-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

6000000 participants

Study Classification

OBSERVATIONAL

Study Start Date

1996-12-31

Study Completion Date

2017-12-31

Brief Summary

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Study of incidence and risk factors of staphylococcus aureus bacteremia in patients with rheumatoid arthritis compared with the general population in a nationwide cohort of all adult members of the population from 1996 until 2017 using national registries

Detailed Description

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Conditions

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Rheumatoid Arthritis Staphylococcus Aureus Bacteremia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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RA patients

Incident patients with rheumatoid arthritis as identified by the Danish National Patient Registry and the rheumatology registry, DANBIO.

Risk factors in RA cohort

Intervention Type OTHER

General population

All other adults, as Identified by the Civil Registration System. Patients who develop RA contribute person-years in the general population cohort until RA diagnosis

Risk factors in general population

Intervention Type OTHER

Interventions

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Risk factors in RA cohort

Intervention Type OTHER

Risk factors in general population

Intervention Type OTHER

Other Intervention Names

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DMARDs (biologic and synthetic) Corticosteroids RA disease activity RA disease duration Tobacco use Joint erosions Prosthetic joints Other comorbid conditions and surgical/dialysis procedures Prosthetic joints Other comorbid conditions and surgical/dialysis procedures

Eligibility Criteria

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Inclusion Criteria

* All members of the adult Danish population

Exclusion Criteria

* Staphylococcus aureus bacteremia prior to inclusion.
* Rheumatoid arthritis diagnosed prior to inclusion.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

University of Aarhus

OTHER

Sponsor Role collaborator

Statens Serum Institut

OTHER

Sponsor Role collaborator

Sabine Dieperink

OTHER

Sponsor Role lead

Responsible Party

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Sabine Dieperink

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

References

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Dieperink SS, Glintborg B, Oestergaard LB, Norgaard M, Benfield T, Mehnert F, Petersen A, Hetland ML. Risk factors for Staphylococcus aureus bacteremia in patients with rheumatoid arthritis and incidence compared with the general population: protocol for a Danish nationwide observational cohort study. BMJ Open. 2019 Sep 3;9(9):e030999. doi: 10.1136/bmjopen-2019-030999.

Reference Type DERIVED
PMID: 31481566 (View on PubMed)

Other Identifiers

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RA-SAB2018

Identifier Type: -

Identifier Source: org_study_id

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