Impact of Germicidal Light

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-01

Study Completion Date

2024-12-31

Brief Summary

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Visible light at 405nm has been shown to be germicidal. The hypothesis is that use of this light (Indigo-Clean Lights) in operating rooms will reduce S. aureus transmission occurring within and between patients and reduce surgical site infections (SSIs). Investigators will evaluate a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without germicidal lights.

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Detailed Description

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Operating room S. aureus exposure has been directly linked to postoperative infections and is therefore an important target for infection prevention. Visible light at 405nm has been shown to be germicidal. Investigators plan to install ambient, germicidal lighting (Indigo-Clean Lights) that uses this wavelength in 4 operating rooms. Patients will undergo surgery according to usual practice. Investigators will conduct a case-control study where patients undergoing surgery with the lights are matched with patients undergoing surgery without the germicidal lights. Patients will be matched by procedure then case duration then American Society of Anesthesiologists (ASA) physical status health classification. These patients will undergo infection surveillance. Infection surveillance will involve use of National Healthcare Safety Network (NHSN) checklists applied to patients who are positive for one or more of the initial screening criteria (elevated white blood cell count, fever (\>38.4 degrees Celsius), office note documentation of infection, positive culture (sputum, blood, urine, wound, other body fluid), or anti-infective order within the 90 postoperative day period.

Conditions

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Bacterial Transmission S.Aureus Transmission Operating Room Exposure to S. Aureus 90-day Postoperative Surgical Site Infections, Superficial and Deep

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Prospective Cohort Study

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Control

The control arm will be surgical care according to usual practice with usual ambient lighting

Group Type NO_INTERVENTION

No interventions assigned to this group

Treatment Arm

The treatment arm will include surgical care according to usual practice with germicidal ambient lighting

Group Type EXPERIMENTAL

Germicidal lighting

Intervention Type DEVICE

Germicidal ambient lighting

Interventions

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Germicidal lighting

Germicidal ambient lighting

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult, at least 18 years old
* Adult patients undergoing orthopedic, cardiothoracic, gyn/onc, and neuro surgery and general anesthesia according to usual care with peripheral and/or central venous access.

Exclusion Criteria

* Pediatric (\<18 years old),
* Incarcerated, and/or
* Pregnant patients
* Undergoing surgery and/or without peripheral or central venous access.
* Undergoing surgery outside of the classifications above

Minimum Eligible Age

18 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes