FErtility, PrEgnancy, contRaceptIon After Breast Cancer in France

NCT ID: NCT03884413

Last Updated: 2025-08-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

517 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-08

Study Completion Date

2022-03-08

Brief Summary

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FErtility, PrEgnancy, contRaceptIon after breast Cancer in France

Detailed Description

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Breast cancer is the most common cancer among women. With the increase of the survival rates, a growing attention is paid to the side effects of the treatments, particularly chemotherapy-induced infertility.

The FEERIC study will give insights into spontaneous fertility outcomes following breast cancer in comparison with a control cohort and will provide data to help patients counselling towards spontaneous fertility rates following breast cancer. It will also provide data on contraceptive prevalence and unintended pregnancy rates in French breast cancer survivors. Reasons for unmet need for family planning will be deciphered, in order to point out pitfalls (lack of patient's information or orientation/ignorance of contraception methods available/topic insufficiently or not discussed with the physician/ lack of family planning offer etc…); and target the appropriate actions to lead (oncologist and oncology nurses education/ dedicated consultations in breast cancer centers/etc…).

Conditions

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Breast Cancer Female

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Breast cancer survivors

Study of spontaneous fertility outcomes following breast cancer history

questionnaires

Intervention Type OTHER

Longitudinal observational study. Collection of health data using self-administered questionnaires online.

Control group

Study of spontaneous fertility outcomes in healthy volonteers population

questionnaires

Intervention Type OTHER

Longitudinal observational study. Collection of health data using self-administered questionnaires online.

Interventions

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questionnaires

Longitudinal observational study. Collection of health data using self-administered questionnaires online.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* females aged from 18 to 43 at inclusion
* previous diagnosis of breast cancer and time from diagnosis comprised between one and five years or women free from breast cancer or other malignancy (healthy volunteers) .

Exclusion Criteria

* hysterectomy and/or bilateral oophorectomy and/or bilateral salpingectomy
* healthy volonteer with history of malignant disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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seintinelles network

UNKNOWN

Sponsor Role collaborator

Institut Curie

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anne-Sophie HAMY-PETIT, MD

Role: PRINCIPAL_INVESTIGATOR

Institut Curie

Locations

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Seintinelles.Com

Paris, , France

Site Status

Countries

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France

References

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Mangiardi-Veltin M, Sebbag C, Rousset-Jablonski C, Ray-Coquard I, Berkach C, Laot L, Wang Y, Abdennebi I, Labrosse J, Sautter C, Toussaint A, Sablone L, Laas E, Khallouch S, Coussy F, Santulli P, Chapron C, Bobrie A, Jacot W, Sella N, Dumas E, Senechal-Davin C, Espie M, Giacchetti S, Maitrot L, Plu-Bureau G, Coutant C, Guerin J, Asselain B, Fumoleau P, Rodrigues M, Decanter C, Mailliez A, Delrieu L, Lemoine A, Jouannaud C, Houdre D, Reyal F, Hamy AS; Seintinelles Research Network. Pregnancy, fertility concerns and fertility preservation procedures in a national study of French breast cancer survivors. Reprod Biomed Online. 2022 Jun;44(6):1031-1044. doi: 10.1016/j.rbmo.2021.12.019. Epub 2022 Jan 19.

Reference Type RESULT
PMID: 35525718 (View on PubMed)

Other Identifiers

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IC 2016-07

Identifier Type: -

Identifier Source: org_study_id

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