Sweat and Gas Sensor for Healthy Skin and Atopic Dermatitis

NCT ID: NCT03874039

Last Updated: 2022-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-15

Study Completion Date

2021-08-10

Brief Summary

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Pilot study of a wearable gas and sweat skin sensor

Detailed Description

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The objective of this study is exploratory and deploys two wearable sweat and gas sensors which detect the composition of sweat proteins and volatile gases emitted from the skin in healthy subjects and patients with atopic dermatitis.

Conditions

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Healthy Adults Atopic Dermatitis Wearables Sweat Sensor Gas Sensor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy Adults

Healthy adults with no prior diagnosis of atopic dermatitis

Gas sensor

Intervention Type DEVICE

The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin.

Sweat Sensor

Intervention Type DEVICE

The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film.

Atopic Dermatitis

Adults with prior diagnosis of Atopic Dermatitis from board certified dermatologist

Gas sensor

Intervention Type DEVICE

The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin.

Sweat Sensor

Intervention Type DEVICE

The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film.

Interventions

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Gas sensor

The gas sensor is an airtight gas capsule attached with a floating solid phase microextraction (SPME) tube. SPME uses a fiber coated with a nontoxic liquid (polymer), and a nontoxic solid (sorbent). The fiber coating extracts the compounds from the gas being released from the skin. Only the glass sample is in contact with the skin.

Intervention Type DEVICE

Sweat Sensor

The sweat sensor is a soft, flexible device that rests on the skin and collects secreted sweat through capillary action. The device is held in place by medical-grade acrylic adhesive film.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age ≥18 years old
* Subjects willing and able to comply with requirements of the protocol
* Healthy adults or subjects with atopic dermatitis

Exclusion Criteria

* Age \<18 years old
* Subjects unwilling and able to comply with requirements of the protocol
* History of skin allergy to medical adhesive tape
* History of heat stroke, heat related or exercise related
* Non-English speaking subjects
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Northwestern University

OTHER

Sponsor Role lead

Responsible Party

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Shuai (Steve) Xu

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shuai Xu, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Locations

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Northwestern University

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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SX09092018

Identifier Type: -

Identifier Source: org_study_id

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