Impact of Pillboxes on Medical Adherence

NCT ID: NCT03861845

Last Updated: 2020-08-26

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-10

Study Completion Date

2019-05-01

Brief Summary

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This study uses an experimental design to test the impact of different types of pillboxes on medication adherence. Participants in this study will randomized to receive one of the three pillbox interventions: 1) A standard seven day a week, one-dose per day pillbox with training 2) an off-the-shelf pillbox that was purchased specifically for the individual's needs with training and education, or 3) a customized 3D printed pillbox that was designed and manufactured specifically to the individual's needs with training and education. Participants will have three visits with the research team to collect baseline data, receive the pillbox, and collect follow up data.

Risks to the study include loss of time, boredom, invasion of privacy, and medication errors. The investigators have taken precautions to mitigate these risks. This study will improve understanding of medication adherence and potentially help us better address poor medication adherence which needlessly causes morbidity, mortality, and costs over $300 million in unnecessary healthcare costs each year.

Detailed Description

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Conditions

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Chronic Disease Medication Adherence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Standard off-the-shelf pillbox

Participants will engage in reflection on medication routines. Then they will receive a standard off-the-shelf pillbox. Finally, the participants will receive education \& training on how to use the pillbox.

Group Type ACTIVE_COMPARATOR

Standard off-the-shelf pillbox

Intervention Type DEVICE

Then the participant will receive a store bought one-dose per day pillbox.

Education & Training

Intervention Type BEHAVIORAL

The participant will receive education and training on how to use the pillbox and how to incorporate the pillbox and taking medications into their daily routine.

Reflection on medication routines

Intervention Type BEHAVIORAL

The participant will reflect on his or her daily routine, medication regimen, and use of existing pillboxes. The participant will also engage in a hands-on standardized pillbox task.

Custom off-the-shelf

Participants will engage in reflection on medication routines. Then they will receive a custom off-the-shelf pillbox. Finally, the participants will receive education \& training on how to use the pillbox.

Group Type EXPERIMENTAL

Custom off-the-shelf pillbox

Intervention Type DEVICE

Then the participant will be administered an off-the-shelf pillbox that was purchased specifically for the participant's preferences, routine, medication regimen, and skills/abilities.

Education & Training

Intervention Type BEHAVIORAL

The participant will receive education and training on how to use the pillbox and how to incorporate the pillbox and taking medications into their daily routine.

Reflection on medication routines

Intervention Type BEHAVIORAL

The participant will reflect on his or her daily routine, medication regimen, and use of existing pillboxes. The participant will also engage in a hands-on standardized pillbox task.

Custom designed and manufactured

Participants will engage in reflection on medication routines. Then they will receive a custom designed and manufactured pillbox. Finally, the participants will receive education \& training on how to use the pillbox.

Group Type EXPERIMENTAL

Custom designed and manufactured pillbox

Intervention Type DEVICE

Then the participant will describe any design preferences for the pillbox. The researcher will design and manufacture the pillbox using a 3D printer, publically available 3D printing object repository, and computer aided design software.

Education & Training

Intervention Type BEHAVIORAL

The participant will receive education and training on how to use the pillbox and how to incorporate the pillbox and taking medications into their daily routine.

Reflection on medication routines

Intervention Type BEHAVIORAL

The participant will reflect on his or her daily routine, medication regimen, and use of existing pillboxes. The participant will also engage in a hands-on standardized pillbox task.

Interventions

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Standard off-the-shelf pillbox

Then the participant will receive a store bought one-dose per day pillbox.

Intervention Type DEVICE

Custom off-the-shelf pillbox

Then the participant will be administered an off-the-shelf pillbox that was purchased specifically for the participant's preferences, routine, medication regimen, and skills/abilities.

Intervention Type DEVICE

Custom designed and manufactured pillbox

Then the participant will describe any design preferences for the pillbox. The researcher will design and manufacture the pillbox using a 3D printer, publically available 3D printing object repository, and computer aided design software.

Intervention Type DEVICE

Education & Training

The participant will receive education and training on how to use the pillbox and how to incorporate the pillbox and taking medications into their daily routine.

Intervention Type BEHAVIORAL

Reflection on medication routines

The participant will reflect on his or her daily routine, medication regimen, and use of existing pillboxes. The participant will also engage in a hands-on standardized pillbox task.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* speak English
* be prescribed to take two or more medications per day, and manage their own medications.

Exclusion Criteria

* have a significant cognitive impairment
* unwilling to use a novel pillbox
* unable to meet with the research team
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Florida International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jaclyn Schwartz, PhD

Role: PRINCIPAL_INVESTIGATOR

Florida International University

Locations

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Florida International University

Miami, Florida, United States

Site Status

Countries

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United States

References

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Schwartz J, Ballard DH. Feasibility of Customized Pillboxes to Enhance Medication Adherence: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2022 Dec;103(12):2288-2295. doi: 10.1016/j.apmr.2022.03.018. Epub 2022 Apr 14.

Reference Type DERIVED
PMID: 35430239 (View on PubMed)

Provided Documents

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Document Type: Informed Consent Form

View Document

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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IRB-18-0451

Identifier Type: -

Identifier Source: org_study_id

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