Blood Transfusion Among Patients With Pelvic Fracture in China
NCT ID: NCT03855644
Last Updated: 2019-02-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
2000 participants
OBSERVATIONAL
2019-04-05
2019-09-01
Brief Summary
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Detailed Description
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2.2 Research content: 2.2.1 Collect basic data, surgical data, blood transfusion related data and patient prognosis related data of patients with pelvic fractures.
2.2.2 Gradually incorporate and exclude data from multiple linear regression models.
2.2.3 Verify the specificity and sensitivity of the intraoperative blood transfusion prediction model.
2.2.4 Create a visualization window to guide clinical blood. 2.2.5 Put into clinical trial and feedback, and continue to verify 2.3 Key issues to be resolved 2.3.1 The factors related to intraoperative blood transfusion in patients with pelvic fractures (such as blood oxygenation, blood loss, HB value, intraoperative autologous blood recovery, blood pressure, heart rate, etc.) were initially screened by univariate analysis.
2.3.2 Reasonably standardize the objective and subjective indicators of different units and different institutions.
2.4 Expected research results Intraoperative blood transfusion prediction model and window for patients with pelvic fractures.
2.5 Assessment indicators Published 1-2 papers. Create a visual applet and put it into trial.
Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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Pelvic fracture patients
(1) 1\<Age\<80, and Chinese residents living in China more than 3 years; (2) Hemoglobin value less than 100g/L during hospitalization; Not suffered from pelvic fracture within 3 months; Not suffer from pathological fractures of the pelvis caused by malignant tumors; without chronic anemia and coagulopathy; accept blood transfusion
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* (2) Hemoglobin value less than 100g/L during hospitalization;
Exclusion Criteria
* (2) Participants who suffer from pathological fractures of the pelvis caused by malignant tumors
* (3) Participants with chronic anemia and coagulopathy
* (4) Participants who rufuse blood transfusion
1 Year
80 Years
ALL
No
Sponsors
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Beijing Shijitan Hospital, Capital Medical University
OTHER
The Affiliated Hospital Of Southwest Medical University
OTHER
Zhejiang Provincial People's Hospital
OTHER
Central South University
OTHER
Qilu Hospital of Shandong University
OTHER
Beijing Aerospace General Hospital
OTHER
The Third Xiangya Hospital of Central South University
OTHER
Responsible Party
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Locations
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Third Xiangya Hospital
Changsha, Hunan, China
Countries
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Central Contacts
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Facility Contacts
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References
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Sathy AK, Starr AJ, Smith WR, Elliott A, Agudelo J, Reinert CM, Minei JP. The effect of pelvic fracture on mortality after trauma: an analysis of 63,000 trauma patients. J Bone Joint Surg Am. 2009 Dec;91(12):2803-10. doi: 10.2106/JBJS.H.00598.
Perkins ZB, Maytham GD, Koers L, Bates P, Brohi K, Tai NR. Impact on outcome of a targeted performance improvement programme in haemodynamically unstable patients with a pelvic fracture. Bone Joint J. 2014 Aug;96-B(8):1090-7. doi: 10.1302/0301-620X.96B8.33383.
Santana-Cabrera L, Rodriguez Gonzalez F, Palacios MS. Delayed perforation of the sigmoid colon following a major pelvic fracture. J Emerg Trauma Shock. 2010 Oct;3(4):425-6. doi: 10.4103/0974-2700.70770. No abstract available.
Carson JL, Terrin ML, Noveck H, Sanders DW, Chaitman BR, Rhoads GG, Nemo G, Dragert K, Beaupre L, Hildebrand K, Macaulay W, Lewis C, Cook DR, Dobbin G, Zakriya KJ, Apple FS, Horney RA, Magaziner J; FOCUS Investigators. Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med. 2011 Dec 29;365(26):2453-62. doi: 10.1056/NEJMoa1012452. Epub 2011 Dec 14.
Nathens AB. Massive transfusion as a risk factor for acute lung injury: association or causation? Crit Care Med. 2006 May;34(5 Suppl):S144-50. doi: 10.1097/01.CCM.0000214309.95032.65.
Ohmori T, Matsumoto T, Kitamura T, Tamura R, Tada K, Inoue T, Hayashi T, Numoto K, Tokioka T. Scoring system to predict hemorrhage in pelvic ring fracture. Orthop Traumatol Surg Res. 2016 Dec;102(8):1023-1028. doi: 10.1016/j.otsr.2016.09.007. Epub 2016 Nov 17.
Hardy JF, de Moerloose P, Samama CM; Members of the Groupe d'Interet en Hemostase Perioperatoire. Massive transfusion and coagulopathy: pathophysiology and implications for clinical management. Can J Anaesth. 2006 Jun;53(6 Suppl):S40-58. doi: 10.1007/BF03022251.
Other Identifiers
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SXKThirdXiangyaHCSU
Identifier Type: -
Identifier Source: org_study_id
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