Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand

NCT ID: NCT03849625

Last Updated: 2022-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

158 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-05-01

Study Completion Date

2020-03-31

Brief Summary

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Study clinical characteristics and phenotypes of patients diagnosed with NSAID sensitivity in Thailand

Detailed Description

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Conditions

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Aspirin Sensitivity Aspirin-exacerbated Respiratory Disease Aspirin-Induced Angioedema-Urticaria Aspirin Allergy NSAID-Induced Asthma NSAID-Induced Angioedema-Urticaria NSAID-Induced Anaphylactoid Reaction Aspirin-Induced Anaphylactoid Reaction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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NSAID sensitivity

Patients diagnosed with an immediate reaction to aspirin/NSAIDs/or paracetamol

aspirin, NSAIDs, paracetamol

Intervention Type DRUG

Perform skin test and/or provocation test with aspirin, paracetmol, or suspected NSAIDs in questionable cases

Interventions

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aspirin, NSAIDs, paracetamol

Perform skin test and/or provocation test with aspirin, paracetmol, or suspected NSAIDs in questionable cases

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Thai patients with a history of an immediate reaction to aspirin/paracetamol, or NSAIDs visiting King Chulalongkorn memorial Hospital

Exclusion Criteria

* None
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chulalongkorn University

OTHER

Sponsor Role lead

Responsible Party

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Assoc. Prof. Jettanong Klaewsongkram, MD.

Assoc. Prof. Jettanong Klaewsongkram, MD.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jettanong Klaewsongkram, MD

Role: PRINCIPAL_INVESTIGATOR

Chulalongkorn University

Locations

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Faculty of Medicine, Chulalongkorn University

Bangkok, , Thailand

Site Status

Countries

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Thailand

References

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Klaewsongkram J, Buranapraditkun S, Mongkolpathumrat P, Palapinyo S, Chantaphakul H. Clinical Characteristics, Urinary Leukotriene E4 Levels, and Aspirin Desensitization Results in Patients With NSAID-Induced Blended Reactions. Allergy Asthma Immunol Res. 2021 Mar;13(2):229-244. doi: 10.4168/aair.2021.13.2.229.

Reference Type RESULT
PMID: 33474858 (View on PubMed)

Other Identifiers

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Chula-ARC 002/13

Identifier Type: -

Identifier Source: org_study_id

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