The Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-375

NCT ID: NCT03848637

Last Updated: 2019-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE1

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-14

Study Completion Date

2019-05-01

Brief Summary

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The purpose of this clinical trial is to evaluate the pharmacokinetics and safety/tolerability after oral administration of CKD-375 and D387 in healthy adults.

Detailed Description

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Conditions

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Type 2 Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group 1

* Period 1: D387 (reference drug)
* Period 2: CKD-387 (test drug)

Group Type EXPERIMENTAL

CKD-375

Intervention Type DRUG

Test drug

D387

Intervention Type DRUG

Reference drug

Group 2

* Period 1: CKD-387 (test drug)
* Period 2: D387 (reference drug)

Group Type EXPERIMENTAL

CKD-375

Intervention Type DRUG

Test drug

D387

Intervention Type DRUG

Reference drug

Interventions

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CKD-375

Test drug

Intervention Type DRUG

D387

Reference drug

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Healthy adults aged 19 to 55 years
2. Females who are not pregnant or breastfeeding or who have surgical infertility
3. Signed informed consent form

Exclusion Criteria

1. History of clinically significant hepatic, renal, nervous, immune, respiratory, endocrine, hemato-oncology, cardiovascular systemic disease or psychosis disorder
2. Clinical laboratory test values are outside the accepted normal range at Screening
3. Current smokers or those who cannot quit smoking during the period from 90 days before the first IP dosing to the last discharge.
4. Subject who drink excessive caffeine or alcohol continuously and who cannot discontinue caffeine or alcohol intake during the period from 3 days before the first IP dosing to the last discharge.
5. Participated in a clinical trial within 90 days prior to 1st IP dosing
6. Not eligible to participate for the study at the discretion of Investigator
Minimum Eligible Age

19 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chong Kun Dang Pharmaceutical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kyung-Sang Yu, M.D., Ph.D

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Central Contacts

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Kyung-Sang Yu, M.D.,Ph.D

Role: CONTACT

+82-2-2072-1920

Soyoung Lee, Pharmacist

Role: CONTACT

+82-2-740-8872

Other Identifiers

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192BE18036

Identifier Type: -

Identifier Source: org_study_id

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