Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata

NCT ID: NCT03847441

Last Updated: 2019-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-01

Study Completion Date

2018-12-31

Brief Summary

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Alopecia Areata is a common condition. This study investigated the efficacy of calcipotriol versus Narrow Band Ultraviolet B in treatment of Alopecia areata and their effects on serum vitamin D3 levels.

Detailed Description

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Conditions

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Alopecia Areata

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Group I

Group Type ACTIVE_COMPARATOR

Calcipotriol

Intervention Type DRUG

Calcipotriol ointment (0.005%)

vitamin D3 level

Intervention Type DIAGNOSTIC_TEST

vitamin D3 (ng/ml)

Group II

Group Type ACTIVE_COMPARATOR

Narrow Band UVB

Intervention Type DEVICE

NB-UVB (311nm) phototherapy

vitamin D3 level

Intervention Type DIAGNOSTIC_TEST

vitamin D3 (ng/ml)

Group III

Group Type ACTIVE_COMPARATOR

Calcipotriol

Intervention Type DRUG

Calcipotriol ointment (0.005%)

Narrow Band UVB

Intervention Type DEVICE

NB-UVB (311nm) phototherapy

vitamin D3 level

Intervention Type DIAGNOSTIC_TEST

vitamin D3 (ng/ml)

Group IV

Group Type PLACEBO_COMPARATOR

vitamin D3 level

Intervention Type DIAGNOSTIC_TEST

vitamin D3 (ng/ml)

Interventions

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Calcipotriol

Calcipotriol ointment (0.005%)

Intervention Type DRUG

Narrow Band UVB

NB-UVB (311nm) phototherapy

Intervention Type DEVICE

vitamin D3 level

vitamin D3 (ng/ml)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Alopecia Areata of scalp

Exclusion Criteria

Other causes of alopecias including scarring alopecia, androgenic alopecia, telogen effluvium autoimmune diseases, pregnant and lactating females
Minimum Eligible Age

14 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aswan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Moustafa A. El Taieb

Head of Dermatology, Venereology and Andrology Department, Ass. Prof. Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Aswan University Hospital

Aswān, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Alopecia Calcipotiol

Identifier Type: -

Identifier Source: org_study_id

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