Blood Sampling of Healthy Volunteers for Immunological Research

NCT ID: NCT03819829

Last Updated: 2023-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-05

Study Completion Date

2027-12-02

Brief Summary

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This protocol will be used to collect crucial components of the immune system from healthy volunteers for the characterization of immune cells in fresh blood. A pipeline has been set up for comprehensive immune phenotyping of both lymphoid and myeloid cells within 24 hours after blood withdrawal.

Detailed Description

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In order to properly compare the immunobiology of healthy volunteers to (advanced) cancer patients, the investigators use age-matched controls with no history of cancer and no potentially interfering medication.

Healthy volunteers will be asked to donate 5 tubes of blood

Conditions

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Healthy Volunteers

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Blood sample

Blood sample

Group Type OTHER

Blood sample

Intervention Type OTHER

Blood sample

Interventions

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Blood sample

Blood sample

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age above 35 years
* Written informed consent
* No history of cancer
* No use of systemic immunosuppressive medication (eg. corticosteroids). Local use of corticosteroids (eg. topical or inhalation) is allowed.

Exclusion Criteria

* Fever 14 days before blood withdrawal
* Donated blood for the same program within the last 2 years
* Pregnancy
Minimum Eligible Age

36 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Netherlands Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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M Kok, MD

Role: PRINCIPAL_INVESTIGATOR

NKI-AvL

Locations

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NKI-AVL

Amsterdam, , Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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M Kok, MD

Role: CONTACT

3120512 ext. 9111

L Voorwerk, MD

Role: CONTACT

3120512 ext. 9111

Facility Contacts

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M Kok, MD

Role: primary

L Voorwerk, MD

Role: backup

Other Identifiers

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B18HIR

Identifier Type: -

Identifier Source: org_study_id

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