E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe
NCT ID: NCT03818503
Last Updated: 2025-03-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
2000 participants
OBSERVATIONAL
2019-06-24
2026-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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OligoCare
Patients with oligometastatic disease treated with radical radiotherapy
No interventions assigned to this group
ReCare
Patients treated with high-dose Re-irradiation
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Written informed consent for E²-RADIatE according to applicable legal and ethical requirements
* Planned use of radiotherapy
* Eligibility of the patient confirmed for at least one cohort confirmed
* Patients of 12 years and older
12 Years
ALL
No
Sponsors
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European Organisation for Research and Treatment of Cancer - EORTC
NETWORK
Responsible Party
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Locations
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Medical University of Graz - Radio-oncology
Graz, , Austria
Ordensklinikum Linz-Barmherzige Schwestern
Linz, , Austria
Universitaetskliniken der Uni Wien - Universitaetsklinikum Wien - AKH unikliniken
Vienna, , Austria
Onze Lieve Vrouw Ziekenhuis
Aalst, , Belgium
Cliniques Universitaires Saint-Luc
Brussels, , Belgium
Institut Jules Bordet
Brussels, , Belgium
Universitair Ziekenhuis Gent
Ghent, , Belgium
AZ Sint-Lucas & Volkskliniek
Ghent, , Belgium
AZ Groeninge Kortrijk - Campus Kennedylaan
Kortrijk, , Belgium
U.Z. Leuven - Campus Gasthuisberg
Leuven, , Belgium
C.H.U. Sart-Tilman
Liège, , Belgium
CHU Site Sainte-Elisabeth-UCL Namur
Namur, , Belgium
AZ Turnhout - Campus Sint Elisabeth
Turnhout, , Belgium
GasthuisZusters Antwerpen - Sint-Augustinus
Wilrijk, , Belgium
University Hospital Hradec Kralove
Hradec Králové, , Czechia
Clinique Pasteur-Lanroze (1174)
Brest, , France
Universitaetsklinikum Aachen AOR - Medizinische Fakultaet der RWTH
Aachen, , Germany
Klinikum Bayreuth Gmbh
Bayreuth, , Germany
Universitaetsklinikum Carl Gustav Carus
Dresden, , Germany
Kliniken Maria Hilf GmbH
Mönchengladbach, , Germany
Ludwig-Maximilians-Universitaet Muenchen - Campus Grosshadern
München, , Germany
St Luke Hospital & SLRON - SLRON - St. Luke'S Hospital Rathgar
Dublin, , Ireland
Beacon Hospital
Dublin, , Ireland
University Hospital Galway
Galway, , Ireland
Sheba Medical Center Tel Hashomer
Ramat Gan, , Israel
Ente Ecclesiastico Ospedale Generale Regionale "F. Miulli"
Acquaviva delle Fonti, , Italy
USL Toscana South East, Ospedale S. Donato
Arezzo, , Italy
Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Brescia, , Italy
Univ. of Florence -Azienda Ospedaliero-Universitaria Careggi
Florence, , Italy
Istituto Clinico Humanitas
Milan, , Italy
IRCCS Ospedale San Raffaele
Milan, , Italy
Istituto Europeo di Oncologia
Milan, , Italy
Sacro Cuore Hospital
Negrar, , Italy
IRCCS Ospedale Sacro Cuore Don Calabria
Negrar, , Italy
Istituti Clinici Scientifici Maugeri
Pavia, , Italy
Centro Nazionale di Adroterapia Oncoloica par il trattamento dei tumori
Pavia, , Italy
San Maria della Misericordia Hospital
Perugia, , Italy
Policlinico Universitario Campus Bio-Medico- Oncology Center
Roma, , Italy
Fondazione Policlinico Universitario A. Gemelli - Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, , Italy
Azienda Ospedaliera Santa Maria di Terni
Terni, , Italy
Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Universita Di Torino - San Giovanni Battista
Torino, , Italy
Stichting Catharina Ziekenhuis
Eindhoven, , Netherlands
University Medical Center Groningen
Groningen, , Netherlands
Radboudumc - Radboud University Medical Center Nijmegen
Nijmegen, , Netherlands
Radiotherapiegroep Arnhem
Nijmegen, , Netherlands
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Lodzi
Lodz, , Poland
Kliniki Neuroradiochirurgii Sp. z o.o.-Radomskie Centrum Onkologii
Radom, , Poland
Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska-Curie National Research Institute of Oncology
Warsaw, , Poland
The Institute Of Oncology
Ljubljana, , Slovenia
ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia)
Badalona, , Spain
Hospital Universitari Vall d'Hebron -Vall d'Hebron Institut Oncologia
Barcelona, , Spain
Hospital De La Santa Creu I Sant Pau
Barcelona, , Spain
Hospital General Universitario Santa Lucia
Cartagena, , Spain
Hospital Universitario Reina Sofia
Córdoba, , Spain
Hospital Universitario Ramon y Cajal
Madrid, , Spain
Hospital Universitario La Paz
Madrid, , Spain
Hospitales HM Sanchinarro-CIOCC
Madrid, , Spain
Hospital Universitario de La Princesa
Madrid, , Spain
Hospital Universitario San Carlos
Madrid, , Spain
Hospital Universitario de Navarra
Pamplona, , Spain
Hospital Universitario de Salamanca (430)
Salamanca, , Spain
Hospital Consorci Sanitari De Terrassa
Terrassa, , Spain
Hospital Clinico Universitario De Valencia
Valencia, , Spain
Hospital Universitario La Fe
Valencia, , Spain
Inselspital
Bern, , Switzerland
Kantonsspital Graubuenden
Chur, , Switzerland
Hôpitaux universitaires de Genève - HUG - site de Cluse-Roseraie
Geneva, , Switzerland
Reseau Hospitalier Neuchatelois - RHNe - La Chaux de Fonds
La Chaux-de-Fonds, , Switzerland
Hopital du Valais - Hopital de Sion
Sion, , Switzerland
UniversitaetsSpital Zurich
Zurich, , Switzerland
NHS Grampian - Aberdeen Royal Infirmary
Aberdeen, , United Kingdom
Velindre NHS Trust - Velindre Cancer Centre
Cardiff, , United Kingdom
NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital
Glasgow, , United Kingdom
The Christie NHS Foundation trust - The Christie NHS Foundation Trust
Manchester, , United Kingdom
The Clatterbridge cancer Center NHS foundation Trust - Clatterbridge Cancer Center - Wirral
Metropolitan Borough of Wirral, , United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital
Sheffield, , United Kingdom
Somerset NHS Foundation Trust-Musgrove Park Hospital
Taunton, , United Kingdom
Countries
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Central Contacts
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References
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Christ SM, Alongi F, Ricardi U, Scorsetti M, Livi L, Balermpas P, Lievens Y, Braam P, Jereczek-Fossa BA, Stellamans K, Ratosa I, Widder J, Peulen H, Dirix P, Bral S, Ramella S, Hemmatazad H, Khanfir K, Geets X, Jeene P, Zilli T, Fournier B, Ivaldi GB, Clementel E, Fortpied C, Oppong FB, Ost P, Guckenberger M. Cancer-specific dose and fractionation schedules in stereotactic body radiotherapy for oligometastatic disease: An interim analysis of the EORTC-ESTRO E2-RADIatE OligoCare study. Radiother Oncol. 2024 Jun;195:110235. doi: 10.1016/j.radonc.2024.110235. Epub 2024 Mar 19.
Nieder C, Willmann J, Andratschke NH. Prospective randomized clinical studies involving reirradiation: update of a systematic review. Strahlenther Onkol. 2023 Sep;199(9):787-797. doi: 10.1007/s00066-023-02118-1. Epub 2023 Jul 27.
Other Identifiers
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EORTC-1811
Identifier Type: -
Identifier Source: org_study_id
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