Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
56 participants
INTERVENTIONAL
2012-06-01
2014-07-31
Brief Summary
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Detailed Description
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Methods: the study was carried out at the department of Ophthalmology, Menoufia university Hospital, Egypt, between June 2012 to July 2014. Fifty-six patients who were diagnosed with primary acquired NLDO. Patients were randomly allocated into two groups: thirty cases underwent external DCR and twenty-six cases underwent silicone intubation with MMC.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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external DCR
A curvilinear incision of 10-15 mm length was made along the anterior lacrimal crest .
The smaller end of the blunt dissector was used to fracture Lamina papyracea, the parchment like bone of the posterior half of the lacrimal fossa. the nasal mucosa was stripped from lacrimal bone with the help of Traquair's periosteal elevator, An osteotomy of approximately 12.5 x10mm was created with successive punching of bone by Cittelli's punch. Lacrimal sac and nasal mucosa were opened in a 'H' fashion with the no.11 Bard-Parker blade and Bowman's probe was in place, to form a large anterior and smaller posterior flap.
external dacryocystorhinostomy
external DCR under general anesthesia with standard sterilization procedures.
canalicular silicone intubation with MMC
canalicular silicone intubation with MMC under general anesthesia with standard sterilization procedures.
silicone intubation with MMC
Bowman's probe was gently inserted into the inferior canalicular system, until a hard stop was felt in the lacrimal sac, after which it was rotated into the NLD to reach below the inferior concha. The probe was then withdrawn via the inferior punctum and the process was repeated for the upper canaliculus.
After irrigation with normal saline to confirm duct patency, irrigation was performed by introducing 1 ml of MMC (0.5 mg/ml) into the duct with a syringe, the ocular surface then irrigatedby normal saline. Intubation was done by a silicone tube connected by each of its end to a malleable steel guide. A grooved director was placed under the inferior turbinate to guide the probe out of the nose, after which the steel guide was cut from the silicone tube
external dacryocystorhinostomy
external DCR under general anesthesia with standard sterilization procedures.
canalicular silicone intubation with MMC
canalicular silicone intubation with MMC under general anesthesia with standard sterilization procedures.
Interventions
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external dacryocystorhinostomy
external DCR under general anesthesia with standard sterilization procedures.
canalicular silicone intubation with MMC
canalicular silicone intubation with MMC under general anesthesia with standard sterilization procedures.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
21 Years
60 Years
ALL
No
Sponsors
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Menoufia University
OTHER
Responsible Party
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Amin Faisal Ellakwa
assistant professor
Other Identifiers
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Ebsar ophthalmic Center
Identifier Type: -
Identifier Source: org_study_id