CT Carcinogenic Risk in Patients With Appendicitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

1000000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-15

Study Completion Date

2021-05-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare the incidence rate of leukemia between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Abdomen CT and Open Appendicectomy：New Diagnostic and Surgical Procedures

NCT02574364

Wound Infection Complication Scar

COMPLETED NA

Colonography Versus Colonoscopy in High Risk Patient

NCT00748449

Colorectal Cancer

TERMINATED NA

Fatigue and QoL Among Gastric Cancer Patients Undergoing Abdominal Surgery

NCT03766945

Gastric Cancer Surgical Wound Infection Fatigue +1 more

UNKNOWN

Appendectomy and Colorectal Cancer

NCT06091137

Colorectal Cancer Appendicitis

UNKNOWN

Retrospective Acute Care Appendectomy Study

NCT06624215

Acute Appendicitis

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

South Korea has a single-payer healthcare system, administered by National Health Insurance Service (NHIS). As healthcare providers in South Korea need to claim reimbursement to NHIS for the vast majority of diagnostic and therapeutic procedures, the NHIS database enabled us to construct a large cohort who did or did not undergo CT for appendicitis. The purpose of this study is to compare the incidence rate of cancer between CT-exposed and CT-unexposed group in patients who underwent appendectomy in South Korea.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Computed Tomography Carcinogenesis Radiation Exposure Appendicitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

CT-exposed group

Abdomen CT

Intervention Type RADIATION

Patients are divided into CT-exposed or unexposed group according to the presence of claims codes of abdominopelvic CT conducted within seven days before and after appendectomy. The seven-day threshold is arbitrarily determined considering the delay in the diagnosis of appendicitis and the postoperative examination for surgical complication.

CT-unexposed group

Abdomen CT

Intervention Type RADIATION

Patients are divided into CT-exposed or unexposed group according to the presence of claims codes of abdominopelvic CT conducted within seven days before and after appendectomy. The seven-day threshold is arbitrarily determined considering the delay in the diagnosis of appendicitis and the postoperative examination for surgical complication.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Abdomen CT

Patients are divided into CT-exposed or unexposed group according to the presence of claims codes of abdominopelvic CT conducted within seven days before and after appendectomy. The seven-day threshold is arbitrarily determined considering the delay in the diagnosis of appendicitis and the postoperative examination for surgical complication.

Intervention Type RADIATION

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients will be entered in the cohort on the date of appendectomy under the diagnosis of appendicitis

Exclusion Criteria

* (a) patients who had a cancer diagnosis before the date of appendectomy,
* (b) those who had prior experience of CT examination more than 7 days before appendectomy,
* (c) those who had syndromes or diseases predisposing cancers,
* (d) those whose diagnosis was changed to appendiceal cancer and
* (e) those whose follow-up duration was shorter than a lag period.

Eligible Sex

ALL

Accepts Healthy Volunteers

No