Genetic Analysis of Pediatric Psoriasis

NCT ID: NCT03768284

Last Updated: 2022-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

86 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-17

Study Completion Date

2021-12-30

Brief Summary

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This study will ascertain approximately 150 subjects, which will include pediatric psoriasis patients diagnosed before age 12, parents not affected by psoriasis, and if a family history is indicated, up to third-degree family members. Saliva (or buccal swabs in the case of infants) will be obtained for DNA isolation.

Detailed Description

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Conditions

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Psoriasis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Psoriasis patients

Patients (of any age) who developed psoriasis before 12 years of age and who have no family history of psoriasis in either parent.

Saliva or buccal sample

Intervention Type OTHER

Saliva or buccal sample

Parents of psoriasis patients

Parents of patients who developed psoriasis before 12 years of age

Saliva or buccal sample

Intervention Type OTHER

Saliva or buccal sample

Up to third-degree family members with or without psoriasis

Up to third-degree family members (first cousin, grandparent, great-grandparent) with or without psoriasis, if family history is indicated.

Saliva or buccal sample

Intervention Type OTHER

Saliva or buccal sample

Interventions

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Saliva or buccal sample

Saliva or buccal sample

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients (of any age) who developed psoriasis before 12 years of age and who have no family history of psoriasis in either parent.
* Parents of patients who developed psoriasis before 12 years of age
* Up to third-degree family members (first cousin, grandparent, great-grandparent) with or without psoriasis, if family history is indicated.

Exclusion Criteria

* Patients, parents, and other family member unable to give a saliva or buccal swab sample.
* Patients, parents, and other family member unable to give written informed consent.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Psoriasis Foundation

OTHER

Sponsor Role collaborator

Icahn School of Medicine at Mount Sinai

OTHER

Sponsor Role collaborator

Northwestern University

OTHER

Sponsor Role lead

Responsible Party

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Amy Paller

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amy Paller, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Locations

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Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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2018-2259

Identifier Type: -

Identifier Source: org_study_id

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