Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases

NCT ID: NCT03767179

Last Updated: 2020-06-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-01-01
• Study Completion Date: 2018-05-15

Brief Summary

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

Detailed Description

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

Conditions

Abortion, Missed

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

Study Group

The study group consisted of 30 fertile, under 35 years old women who were included in the study for the first time missed abortus diagnosis.

study

Intervention Type: DIAGNOSTIC_TEST

procalcitonin, sedimentation, CRP, leukocyte identification

Control Group

30 cases with the same trimester, fertile, and under 35 years old who were referred to Obstetrics clinic, who had no systemic disease, were included in the study.

study

Intervention Type: DIAGNOSTIC_TEST

procalcitonin, sedimentation, CRP, leukocyte identification

Interventions

study

procalcitonin, sedimentation, CRP, leukocyte identification

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

Exclusion Criteria

• Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
• Smoking
• Rejection to participate in the study.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Karadeniz Technical University

OTHER

Sponsor Role: lead

Responsible Party

Suleyman Guven

Clinical Professor.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Suleyman Guven, Prof

Role: PRINCIPAL_INVESTIGATOR

KaradenizTU Medicine Faculty

Locations

Karadeniz Technical University, Medical Faculty of Medicine.

Trabzon, Ortahisar, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

KTU

Identifier Type: -

Identifier Source: org_study_id