Extinction Learning in Youth With Tourette Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-28

Study Completion Date

2023-08-02

Brief Summary

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Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but have not been directly evaluated in youth with Tourette syndrome (TS). This study examines extinction learning and extinction recall in youth with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

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Detailed Description

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Conditions

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Tourette Syndrome in Children Tourette Syndrome in Adolescence Habit Reversal Training Tic

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Habit Reversal Training

Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics. It will be delivered over 4 two-hour sessions in an intensive format.

Group Type EXPERIMENTAL

Habit Reversal Training

Intervention Type BEHAVIORAL

4 sessions of habit reversal training

Interventions

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Habit Reversal Training

4 sessions of habit reversal training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age 8-17 years (inclusive)
* have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater than 13 (\>9 for youth with motor or vocal tics only)
* have not received more than 4 previous sessions of HRT
* be fluent in English.
* Medication free or on a stable dose of psychiatric medication for 8 weeks prior to enrollment.