In-vitro Effect of Mangosteen Pericarp Extract on Cell Lines
NCT ID: NCT03728192
Last Updated: 2018-11-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
2 participants
INTERVENTIONAL
2016-03-07
2018-07-13
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Mangosteen treated group
HeLa and H357 cell lines were procured and were further subdivided into 2 subdivisions and were assigned interventions:
Mangosteen group- cells treated with mangosteen extract and Camptothecin group - cells treated with standard anticancer drug camptothecin(25 micro mole)
mangosteen extract
For Mangosteen group :DNA fragmentation assay is used to identify apoptosis.1×106 cells were harvested and treated with mangosteen pericarp extract for 48 h For Camptothecin group : Cells were also treated with standard anticancer drug Camptothecin to act as a positive control.
Untreated group
H357 and HeLa cell line without any drug intervention.
No interventions assigned to this group
Interventions
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mangosteen extract
For Mangosteen group :DNA fragmentation assay is used to identify apoptosis.1×106 cells were harvested and treated with mangosteen pericarp extract for 48 h For Camptothecin group : Cells were also treated with standard anticancer drug Camptothecin to act as a positive control.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients with cervical carcinoma
Exclusion Criteria
ALL
No
Sponsors
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Meenakshi Ammal Dental College and Hospital
OTHER
Responsible Party
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Dr.Jaideep Mahendra
Director of post graduate studies
Principal Investigators
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Jaideep Mahendra, MDS,PhD
Role: PRINCIPAL_INVESTIGATOR
Meenakshi academy of higher education and research
Other Identifiers
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MAHER-MU-004-IEC/2016
Identifier Type: -
Identifier Source: org_study_id
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