Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers

NCT ID: NCT03725917

Last Updated: 2019-04-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

143 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-25

Study Completion Date

2019-12-01

Brief Summary

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This study evaluates the effects of a physiotherapy protocol (manual therapy and exercise) in the prevention of diabetic foot ulcers in patients with diabetic neuropathy. A group of participants will receive a physiotherapy protocol added to their usual medical treatment and the other group will not receive physiotherapy treatment.

Detailed Description

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Neuropathic diabetic patients present alterations in joint mobility, plantar pressures and ankle and foot function, characteristics related to the development of ulcers.

In previous studies, it has been observed that physiotherapy protocols have produced improvements in joint mobility, magnitude of plantar pressures, distribution of plantar pressures, and improved function in the ankle and foot.

A 12-week progressive physiotherapy protocol composed of manual therapy and exercise could produce changes in foot and ankle characteristics in diabetic neuropathic patients related to tissue damage, resulting in a reduction in ulcerations.

Conditions

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Diabetic Foot Ulcer Diabetic Neuropathy Peripheral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors
All assessments will be made by an experienced Podiatrist, who will not have other functions in the study

Study Groups

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Experimental Group

The intervention will be a progressive physiotherapy protocol formed by therapeutic exercise and manual therapy

Group Type EXPERIMENTAL

Physiotherapy protocol

Intervention Type OTHER

The intervention will consist of a physiotherapy protocol twice a week for twelve weeks. The protocol will be done in three phases, constituting each month, a phase of the protocol. The first two phases will include therapeutic exercise of progressive difficulty and manual therapy, while the last phase will include only one week of manual therapy and therapeutic exercise, the last three weeks being composed only of therapeutic exercise

Control Group

The control group will not receive physiotherapy treatment.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Physiotherapy protocol

The intervention will consist of a physiotherapy protocol twice a week for twelve weeks. The protocol will be done in three phases, constituting each month, a phase of the protocol. The first two phases will include therapeutic exercise of progressive difficulty and manual therapy, while the last phase will include only one week of manual therapy and therapeutic exercise, the last three weeks being composed only of therapeutic exercise

Intervention Type OTHER

Other Intervention Names

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Physical therapy protocol

Eligibility Criteria

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Inclusion Criteria

* Participants with diabetes mellitus type 1 or type 2
* Patients with diabetic neuropathy
* Patients with no previous history of ulcers
* Patients with no previous history of lower limb amputations

Exclusion Criteria

* Patients with neurological or orthopedic problems that make walking difficult (spasticity, cerebral palsy, poliomyelitis, rheumatoid arthritis)
* Severe vascular complications (arterial or venous ulcers)
* Patients with critical ischemia
* Patient who need walking aids (canes, crutches, splints etc.)
* Patients with a history of neuropathy with different etiology from diabetes mellitus.
* Patients with peripheral nervous lesions (traumatic origin, associated with surgical procedures, compression of spinal roots, plexus palsy, herpes zoster, polyradiculopathy, etc.)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidad Complutense de Madrid

OTHER

Sponsor Role lead

Responsible Party

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Guido Gomez Chiguano

Clinical Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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José L Lázaro Martínez

Role: STUDY_DIRECTOR

Universidad Complutense de Madrid

Locations

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Universidad Complutense de Madrid

Madrid, Madrid, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Guido F Gómez Chiguano

Role: CONTACT

+34 655878395

Mateo López Moral

Role: CONTACT

+34 652 31 15 73

Facility Contacts

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Guido F Gómez Chiguano, Physiotherapist

Role: primary

655878395

References

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Goldsmith JR, Lidtke RH, Shott S. The effects of range-of-motion therapy on the plantar pressures of patients with diabetes mellitus. J Am Podiatr Med Assoc. 2002 Oct;92(9):483-90. doi: 10.7547/87507315-92-9-483.

Reference Type BACKGROUND
PMID: 12381797 (View on PubMed)

Cerrahoglu L, Kosan U, Sirin TC, Ulusoy A. Range of Motion and Plantar Pressure Evaluation for the Effects of Self-Care Foot Exercises on Diabetic Patients with and Without Neuropathy. J Am Podiatr Med Assoc. 2016 May;106(3):189-200. doi: 10.7547/14-095.

Reference Type BACKGROUND
PMID: 27269974 (View on PubMed)

Sartor CD, Hasue RH, Cacciari LP, Butugan MK, Watari R, Passaro AC, Giacomozzi C, Sacco IC. Effects of strengthening, stretching and functional training on foot function in patients with diabetic neuropathy: results of a randomized controlled trial. BMC Musculoskelet Disord. 2014 Apr 27;15:137. doi: 10.1186/1471-2474-15-137.

Reference Type BACKGROUND
PMID: 24767584 (View on PubMed)

Dijs HM, Roofthooft JM, Driessens MF, De Bock PG, Jacobs C, Van Acker KL. Effect of physical therapy on limited joint mobility in the diabetic foot. A pilot study. J Am Podiatr Med Assoc. 2000 Mar;90(3):126-32. doi: 10.7547/87507315-90-3-126.

Reference Type BACKGROUND
PMID: 10740995 (View on PubMed)

Other Identifiers

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V2.0_16.07.18

Identifier Type: -

Identifier Source: org_study_id

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