Study to Estimate the Point Prevalence of Peripheral Intravenous Catheter-related Complications in Brazil

NCT ID: NCT03719287

Last Updated: 2024-10-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

295 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-07

Study Completion Date

2019-10-01

Brief Summary

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A multi-center, national prevalence study where: (1) baseline SPIVC therapy complications of hospitalized adult patients that meet the inclusion/exclusion criteria of the study and (2) the compliance of clinicians to the Hospital's evidence based practice will be measured in Brazil.

Detailed Description

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At each participating research site, select nurse clinicians who are experienced or experts in short peripheral I.V. catheter (SPIVC) therapy, will audit medical records and observe the SPIVC sites of adult patients in various hospital wards until a minimum total of 300 SPIVC sites are audited among 3 Brazilian acute care hospitals. The wards audited will be selected by the Investigator and will be audited during a specified time period until at least 100 SPIVCs are audited. The time to complete the study will depend on the size of the select wards, the number of nurse auditors and the number of monitoring visits required.

There are no treatments. The short peripheral I.V. catheter-related medical devices (products) observed during the study are currently approved by Brazil regulatory agencies, purchased by the hospital and available to the clinician at the time of the study.

Conditions

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Infusion Site Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Hospital #1

Patients who meet inclusion criteria in the first of three participating Brazil hospitals

No interventions assigned to this group

Hospital #2

Patients who meet inclusion criteria in the second of three participating Brazil hospitals

No interventions assigned to this group

Hospital #3

Patients who meet inclusion criteria in the third of the three participating Brazil hospitals

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male or female subject, aged 18 years or older at the time of the study's audit of the ward;
* Subject admitted into one of the wards audited at the study site;
* Subject available for observation at the time of the audit;
* Subject with at least one inserted PIVC;
* Subject that voluntarily signed and dated the informed consent form (ICF) prior to study entry, if required by the study site's Ethics Committee.

Exclusion Criteria

* Subject under treatment at the study site's outpatient clinics;
* Subject admitted into a mental health ward, emergency ward or burn unit;
* Subject awaiting transfer to another facility.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eurotrials Brasil Consultores Cientificos Ltda

INDUSTRY

Sponsor Role collaborator

3M

INDUSTRY

Sponsor Role collaborator

Solventum US LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joaquim Simoes Neto, MD

Role: PRINCIPAL_INVESTIGATOR

Centro de Pequisa Clinica Sao Lucas

Larissa S Victor, RN

Role: PRINCIPAL_INVESTIGATOR

Hospital Erasto Gaertner (HEG)

Ariane F Machado Avelar, PhD

Role: PRINCIPAL_INVESTIGATOR

Federal University of São Paulo

Locations

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Hospital Erasto Gaertner (HEG)

Curitiba, Paraná, Brazil

Site Status

Centro de Pequisa Clinica Sao Lucas

Campinas, São Paulo, Brazil

Site Status

Universidade Federal de Sao Paulo

São Paulo, , Brazil

Site Status

Countries

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Brazil

References

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PR Newswire. Global Peripheral I.V. catheter market 2014-2018.

Reference Type BACKGROUND

Rickard CM, Webster J, Wallis MC, Marsh N, McGrail MR, French V, Foster L, Gallagher P, Gowardman JR, Zhang L, McClymont A, Whitby M. Routine versus clinically indicated replacement of peripheral intravenous catheters: a randomised controlled equivalence trial. Lancet. 2012 Sep 22;380(9847):1066-74. doi: 10.1016/S0140-6736(12)61082-4.

Reference Type BACKGROUND
PMID: 22998716 (View on PubMed)

Webster J, Clarke S, Paterson D, Hutton A, van Dyk S, Gale C, Hopkins T. Routine care of peripheral intravenous catheters versus clinically indicated replacement: randomised controlled trial. BMJ. 2008 Jul 8;337(7662):a339. doi: 10.1136/bmj.a339.

Reference Type BACKGROUND
PMID: 18614482 (View on PubMed)

Bausone-Gazda D, Lefaiver CA, Walters SA. A randomized controlled trial to compare the complications of 2 peripheral intravenous catheter-stabilization systems. J Infus Nurs. 2010 Nov-Dec;33(6):371-84. doi: 10.1097/NAN.0b013e3181f85be2.

Reference Type BACKGROUND
PMID: 21079465 (View on PubMed)

Martinez JA, Piazuelo M, Almela M, Blecua P, Gallardo R, Rodriguez S, Escalante Z, Robau M, Trilla A. Evaluation of add-on devices for the prevention of phlebitis and other complications associated with the use of peripheral catheters in hospitalised adults: a randomised controlled study. J Hosp Infect. 2009 Oct;73(2):135-42. doi: 10.1016/j.jhin.2009.06.031. Epub 2009 Aug 27.

Reference Type BACKGROUND
PMID: 19712998 (View on PubMed)

Maki DG. Improving the safety of peripheral intravenous catheters. BMJ. 2008 Jul 8;337(7662):a630. doi: 10.1136/bmj.a630.

Reference Type BACKGROUND
PMID: 18614483 (View on PubMed)

Wallis MC, McGrail M, Webster J, Marsh N, Gowardman J, Playford EG, Rickard CM. Risk factors for peripheral intravenous catheter failure: a multivariate analysis of data from a randomized controlled trial. Infect Control Hosp Epidemiol. 2014 Jan;35(1):63-8. doi: 10.1086/674398. Epub 2013 Dec 2.

Reference Type BACKGROUND
PMID: 24334800 (View on PubMed)

Alexandrou E, Ray-Barruel G, Carr PJ, Frost S, Inwood S, Higgins N, Lin F, Alberto L, Mermel L, Rickard CM. International prevalence of the use of peripheral intravenous catheters. J Hosp Med. 2015 Aug;10(8):530-3. doi: 10.1002/jhm.2389. Epub 2015 Jun 3.

Reference Type BACKGROUND
PMID: 26041384 (View on PubMed)

Gorski LA, Hadaway L, Hagle ME, Broadhurst D, Clare S, Kleidon T, Meyer BM, Nickel B, Rowley S, Sharpe E, Alexander M. Infusion Therapy Standards of Practice, 8th Edition. J Infus Nurs. 2021 Jan-Feb 01;44(1S Suppl 1):S1-S224. doi: 10.1097/NAN.0000000000000396. No abstract available.

Reference Type BACKGROUND
PMID: 33394637 (View on PubMed)

Mattox EA. Complications of Peripheral Venous Access Devices: Prevention, Detection, and Recovery Strategies. Crit Care Nurse. 2017 Apr;37(2):e1-e14. doi: 10.4037/ccn2017657.

Reference Type BACKGROUND
PMID: 28365664 (View on PubMed)

Helm RE, Klausner JD, Klemperer JD, Flint LM, Huang E. Accepted but unacceptable: peripheral IV catheter failure. J Infus Nurs. 2015 May-Jun;38(3):189-203. doi: 10.1097/NAN.0000000000000100.

Reference Type BACKGROUND
PMID: 25871866 (View on PubMed)

Marsh N, Webster J, Flynn J, Mihala G, Hewer B, Fraser J, Rickard CM. Securement methods for peripheral venous catheters to prevent failure: a randomised controlled pilot trial. J Vasc Access. 2015 May-Jun;16(3):237-44. doi: 10.5301/jva.5000348. Epub 2015 Feb 4.

Reference Type BACKGROUND
PMID: 25656258 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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EM-05-014222

Identifier Type: -

Identifier Source: org_study_id

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