Beta-alanine Supplementation and High-intensity Interval Training

NCT ID: NCT03708185

Last Updated: 2021-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-04

Study Completion Date

2021-06-28

Brief Summary

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The present study will seek to quantify whether a period of HIIT alongside β-alanine supplementation will improve the adaptation to training, and therefore performance, more than a period of HIIT alone.

Detailed Description

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Whilst high-intensity interval training (HIIT) is a powerful stimulus to increase endurance exercise performance, there are potential nutritional interventions that can be put in place to further increase performance gains.

Energy for the contraction of muscles is created in the mitochondria. HIIT can improve the function of mitochondria, therefore improving performance.

Β-alanine is a commonly used supplement that can improve exercise performance by increasing the amount of carnosine in muscle. Carnosine has many functions that may help improve exercise capacity.

The present study will seek to quantify whether a period of HIIT alongside β-alanine supplementation will improve the adaptation to training, and therefore performance, more than a period of HIIT alone.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Doubly-blinded \& randomised using an online randomisation website.

Study Groups

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HIIT + beta-alanine

Participants will ingest an active supplement containing beta-alanine for a period of 12 weeks. During the last 8 weeks of that period, participants will take part in a structured program of high-intensity interval training.

Group Type EXPERIMENTAL

Beta-alanine

Intervention Type DIETARY_SUPPLEMENT

N/A: see arm description

HIIT + placebo

Participants will ingest a placebo supplement containing no beta-alanine for a period of 12 weeks. During the last 8 weeks of that period, participants will take part in a structured program of high-intensity interval training.

Group Type EXPERIMENTAL

Placebo

Intervention Type DIETARY_SUPPLEMENT

N/A: see arm description

Interventions

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Beta-alanine

N/A: see arm description

Intervention Type DIETARY_SUPPLEMENT

Placebo

N/A: see arm description

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Moderately trained (vo2max: 50 - 60 ml/kg/min).
* Females must be taking an oral contraceptive, or using a contraceptive implant.

Exclusion Criteria

* A recent history of musculoskeletal injury
* Diagnosed cardiovascular or metabolic disease
* Regular use of beta-alanine supplements
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Exeter

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Andrew D Davenport, MSc

Role: PRINCIPAL_INVESTIGATOR

The University of Exeter

Locations

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School of Sport and Health Sciences

Exeter, Devon, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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180509/B/02

Identifier Type: -

Identifier Source: org_study_id

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