ARTUS MONO Artificial Urinary Sphincter

NCT ID: NCT03703843

Last Updated: 2018-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

3 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-23

Study Completion Date

2018-09-26

Brief Summary

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The ARTUS MONO implant is an active implantable medical device (AIMD) that assist the urethral sphincter function of female patients suffering from moderate to severe urinary incontinence, by remotely opening and closing a cuff placed around the bladder neck. The purpose of this clinical investigation is to evaluate the feasibility of implantation of the device, its safety and its efficacy, when temporarily implanted in female patients scheduled for anterior pelvic exenteration for bladder cancer.

Detailed Description

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Conditions

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Urinary Incontinence,Stress

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DEVICE_FEASIBILITY

Blinding Strategy

NONE

Study Groups

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Active

ARTUS MONO

Group Type EXPERIMENTAL

ARTUS MONO

Intervention Type DEVICE

Temporarily implant and activation of the medical device

Interventions

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ARTUS MONO

Temporarily implant and activation of the medical device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Female patients aged ≥ 18 yo
2. BMI \> 18,5 and \< 35
3. Patient scheduled for an anterior pelvic exenteration with ileal conduit urinary diversion
4. Signed informed consent

Exclusion Criteria

1. Advanced bladder cancer with bladder neck and/or urethral extension
2. Past pelvic radiation therapy
3. Patient previously treated with an artificial urinary sphincter or other urogenital implant
4. Positive urine culture during the past 2 weeks
5. Indwelling bladder catheter during the past 2 weeks
6. Documented history of sensitivity to silicone
7. History of connectivitis disease
8. Immunosuppressive therapy in the last 3 months
9. Vulnerable subjects
10. Participation in any other clinical investigation
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Myopowers Medical Technologies France SAS

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nicolas BARRY DELONGCHAMPS, PR

Role: PRINCIPAL_INVESTIGATOR

Hôpital Cochin

Locations

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Thomayer hospital

Prague, , Czechia

Site Status

Cochin Hospital

Paris, , France

Site Status

Countries

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Czechia France

Other Identifiers

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ARTUS00

Identifier Type: -

Identifier Source: org_study_id

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