Study of the Effectiveness of ETIASA® (Sustained Release 5-Aminosalicylate) in Maintenance Treatment of Ulcerative Colitis (UC)

NCT ID: NCT03689673

Last Updated: 2021-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

607 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-04-24

Study Completion Date

2020-11-16

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the protocol is to assess the effectiveness of Etiasa® for preventing relapse in Chinese patients with quiescent UC.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ulcerative Colitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Data collection

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Male or Female patient ≥ 18 years old and ≤ 65 years old
* Patient has provided written informed consent to participate in the study after the purpose and nature have been clearly explained to him/her;
* Patient with documented diagnosis of mild-moderate Ulcerative Colitis (UC). The "documented diagnosis" should include a typical histology observed at least once in the course of the disease;
* Have a documented history of UC that has been successfully maintained in complete steroid-free remission for at least 1 month prior to study entry;
* The modified mayo score ≤ 2, without subscore \>1, which is supported by a rectum-sigmoidoscopy or a colonoscopy;
* Regimen of maintenance of remission contains Etiasa®
* Patient mentally and physically able to answer the questionnaire.

Exclusion Criteria

* Have a history of allergy or hypersensitivity to salicylates, 5-aminosalicylates, or any component of Etiasa®;
* Pregnant and breastfeeding women, approaching childbirth female or unwilling to take birth control measures during the study;
* A topical 5-aminosalicylate agent is included in the regimen;
* Patients with infectious colitis (positive for germs, ovum or parasites causing bowel disease);
* Treated with the other study drug at enrollment, or within past 3 months of enrollment;
* Serious underlying disease other than UC which in the opinion of the investigator may interfere with the patient's ability to participate fully in the study;
* Crohn's disease;
* Pancreatitis;
* Known bleeding disorders;
* Potentially unreliable patients, and those judged by the investigator to be unsuitable for the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ipsen

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ipsen Medical Director

Role: STUDY_DIRECTOR

Ipsen

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

The Affiliated Beijing Chao-yang Hospital of Capital Medical University

Beijing, , China

Site Status

Peking University First Hospital

Beijing, , China

Site Status

China-Japan Union Hospital of Jilin University

Changchun, , China

Site Status

The Third Affiliated Hospital of The Third Military Medical University of Chinese PLA

Chongqing, , China

Site Status

The First Affiliated Hospital of Dalian Medical University

Dalian, , China

Site Status

The First Affiliated Hospital of Sun Yatsen University

Guangzhou, , China

Site Status

Nanfang Hospital of Southern Medical University

Guangzhou, , China

Site Status

The Sixth Affiliated Hospital of Sun Yatsen University

Guangzhou, , China

Site Status

Hebi People Hospital

Hebi, , China

Site Status

Anhui Provincial Hospital

Hefei, , China

Site Status

Henan Province People Hospital

Henan, , China

Site Status

The PLA 150 Central Hospital

Luoyang, , China

Site Status

The First Affiliated hospital of Nan Chang University

Nanchang, , China

Site Status

Nanjing General Hospital of Nanjing Military Command

Nanjing, , China

Site Status

Nanjing Drum Tower Hospital

Nanjing, , China

Site Status

Jiangsu Province Hospital of TCM

Nanjing, , China

Site Status

The Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status

Qingdao Municipal Hospital

Qingdao, , China

Site Status

Suzhou Third People Hospital

Suzhou, , China

Site Status

The second affiliated hospital of Suzhou University

Suzhou, , China

Site Status

Tianjin People's Hospital

Tianjin, , China

Site Status

The Second Hospital Affiliated to Wenzhou Medical College

Wenzhou, , China

Site Status

Union Hospital Affiliated to Tongji Medical College

Wuhan, , China

Site Status

The People's Hospital of Wuhan University

Wuhan, , China

Site Status

The First Affiliated Hospital of the Fourth Military Medical University

Xi'an, , China

Site Status

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, , China

Site Status

Countries

Review the countries where the study has at least one active or historical site.

China

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

A-38-58216-001

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

The Colitis Once Daily Asacol Study
NCT00708656 COMPLETED PHASE3