Recurrent Events After Percutaneous Coronary INterventio for ACS

NCT ID: NCT03675347

Last Updated: 2018-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-11-30

Brief Summary

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Patients undergoing PCI for ACS are exposed to a significant ischemic and bleeding risk.

The aim of our study is instead to analyze in detail the rates of recurrent events, but also their predictors and impact on outcomes, in a population of unselected real life patients treated with PCI for ACS discharged on either Clopidogrel, Prasugrel or Ticagrelor who already experienced an adverse event during the first year of follow up.

Detailed Description

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Patients undergoing PCI for ACS are exposed to a significant ischemic and bleeding risk. The rate, predictors and outcomes of an adverse event in this population has been already investigated. However, to the best of our knowledge, only two papers took specifically in analysis rates of recurrence after a first event; the first is a recently published article by Giustino et al; it took in consideration recurrent events in a selected population of patients with ST-elevation Myocardial Infarction (STEMI) participating in the HORIZONS-AMI Trial, discharged on Aspirin and Clopidogrel, analyzing their incidence in the first year of follow-up. The second is a paper by Fanaroff et al which primarily focused on the factors leading to a DAPT intensification in patients with recurrent events.

The aim of our study is instead to analyze in detail the rates of recurrent events, but also their predictors and impact on outcomes, in a population of unselected real life patients treated with PCI for ACS discharged on either Clopidogrel, Prasugrel or Ticagrelor who already experienced an adverse event during the first year of follow up.

Conditions

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Coronary Artery Disease Acute Coronary Syndrome

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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angioplasty

angioplasty

Intervention Type OTHER

Eligibility Criteria

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Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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A.O.U. Città della Salute e della Scienza

OTHER

Sponsor Role lead

Responsible Party

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Fabrizio D'Ascenzo

Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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biole carloalberto, doctor

Role: STUDY_CHAIR

Molinette

Locations

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San Giovanni Battista

Torino, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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dascenzo fabrizio, Doctor

Role: CONTACT

3391390253

brustio alessandro, Doctor

Role: CONTACT

0116335570

Facility Contacts

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fabrizio dascenzo, doctor

Role: primary

3391390253

Other Identifiers

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AGAIN

Identifier Type: -

Identifier Source: org_study_id

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