An Observation Study on Neuropsychology and Serum Melatonin Level in Patients With Medication Overuse Headache
NCT ID: NCT03655184
Last Updated: 2019-06-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
90 participants
OBSERVATIONAL
2017-09-10
2019-06-30
Brief Summary
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Melatonin is a hormone secreted from the pineal gland. Melatonin is an antioxidant, antinociceptive, hypnotic, anticonvulsant, neuroprotective, anxiolytic, sedative and analgesic.
This observational study aims to investigate clinical characteristics of patients with MOH and to explore the relationship between the serum melatonin level and medication overuse headache. Researchers hope to provide a new idea for the clinical treatment of MOH: melatonin can be used as an adjuvant therapy for MOH in the future.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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MOH group
Patients with medication overuse headache
No interventions assigned to this group
Episodic migraine group
Patients with episodic migraine
No interventions assigned to this group
Healthy group
No headache or other special medical history
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Subject has had 1-8 migraines per month over the previous 3 months
* Sign the informed consent
Exclusion Criteria
* History of bleeding disorders
18 Years
65 Years
ALL
Yes
Sponsors
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The First Affiliated Hospital with Nanjing Medical University
OTHER
Responsible Party
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Principal Investigators
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Qi Wan, professor
Role: STUDY_DIRECTOR
The First Affiliated Hospital with Nanjing Medical University
Locations
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Department of Neurology, the First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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References
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Tao H, Wan Q, Sun M, Cai K, Song Y, He M, Shen J. Involvement of Plasma Melatonin in Medication-Overuse Headache: A Cross-Sectional Study. Clin Neuropharmacol. 2024 Jan-Feb 01;47(1):12-16. doi: 10.1097/WNF.0000000000000573. Epub 2023 Oct 19.
Other Identifiers
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2018-SR-239
Identifier Type: -
Identifier Source: org_study_id
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